SCHEMBL10191081

SCHEMBL10191081

Cc1ccc(S(=O)(=O)OCCCCCCNC(=O)OC(C)(C)C)cc1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 13/20 0.61
CA2 P00918 13/20 0.61
CA12 O43570 7/20 0.61
CA9 Q16790 7/20 0.61
TDP1 Q9NUW8 1/20 0.49
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
CCNC P24863 1/20 0.45
CDK8 P49336 1/20 0.45
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29040473 1.00 CA1 (0.61) CA1CA2CA12CA9TDP1
SCHEMBL29040417 1.00 CA1 (0.61) CA1CA2CA12CA9TDP1
SCHEMBL29040410 1.00 CA1 (0.61) CA1CA2CA12CA9TDP1
SCHEMBL4640090 1.00 CA1 (0.61) CA1CA2CA12CA9TDP1
SCHEMBL16930099 1.00 CA1 (0.61) CA1CA2CA12CA9TDP1
SCHEMBL23835564 1.00 CA1 (0.61) CA1CA2CA12CA9TDP1
SCHEMBL2822013 0.99 CA1 (0.60) CA1CA2CA12CA9TDP1
SCHEMBL487585 0.95 CA1 (0.59) CA1CA2CA12CA9TDP1
SCHEMBL17162051 0.94 CA1 (0.55) CA1CA2CA12CA9TDP1
SCHEMBL22326309 0.92 CA1 (0.56) CA1CA2CA12CA9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345446-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2025-11-13 US disclosed
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
US-20250074904-A1 NSD2-TARGETED CHECMICAL DEGRADERTS AND COMPOSITIONS AND METHODS OF USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-03-06 US disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed
US-20230242506-A1 HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS GENENTECHT, INC. (US) 2023-08-03 US disclosed
US-20230167105-A1 BCL-2 PROTEIN INHIBITORS RECURIUM IP HOLDINGS, LLC 2023-06-01 US disclosed
WO-2023091565-A1 NSD2-TARGETED CHEMICAL DEGRADERS AND COMPOSITIONS AND METHODS OF USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-05-25 WO disclosed
WO-2023091565-A1 NSD2-TARGETED CHEMICAL DEGRADERS AND COMPOSITIONS AND METHODS OF USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-05-25 WO disclosed
EP-4107152-A1 BCL-2 PROTEIN INHIBITORS Recurium IP Holdings, LLC (US) 2022-12-28 EP disclosed
US-20220105188-A1 TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2022-04-07 US disclosed
US-20120301894-A1 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS Life Technologies Corporation (US) 2012-11-29 US disclosed
US-8114636-B2 Labeling and detection of nucleic acids Life Technologies Corporation (US) 2012-02-14 US disclosed
US-8114636-B2 Labeling and detection of nucleic acids Life Technologies Corporation (US) 2012-02-14 US disclosed
US-20100261181-A1 LABELING AND DETECTION OF NUCLEIC ACIDS Life Technologies Corporation (US) 2010-10-14 US disclosed
US-20100261181-A1 LABELING AND DETECTION OF NUCLEIC ACIDS Life Technologies Corporation (US) 2010-10-14 US disclosed
US-20080050731-A1 LABELING AND DETECTION OF NUCLEIC ACIDS INVITROGEN CORPORATION (US) 2008-02-28 US disclosed
US-20080050731-A1 LABELING AND DETECTION OF NUCLEIC ACIDS INVITROGEN CORPORATION (US) 2008-02-28 US disclosed
US-20070249014-A1 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS INVITROGEN CORPORATION (US) 2007-10-25 US disclosed
WO-2007082897-A2 POLYSACCHARIDE-CYCLODEXTRIN CONJUGATES B. BRAUN MELSUNGEN AG (DE) 2007-07-26 WO disclosed
EP-1808181-A1 Polysaccharide-cyclodextrin conjugates B. BRAUN MELSUNGEN AG (DE) 2007-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220105188-A1 TARGET PROTEIN EED DEGRADATION-INDUCING DEGRADUCER, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASES RELATED TO EED, EZH2, OR PRC2, COMPRISING SAME AS ACTIVE INGREDIENT EED, VHL, CUL1 CA1 2108/4885CA2 3802/4885CA12 3934/4885
US-20250345446-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES SORT1, SCARB1, LAMP1 CA1 4441/4885CA2 4158/4885CA12 4066/4885
US-20250074904-A1 NSD2-TARGETED CHECMICAL DEGRADERTS AND COMPOSITIONS AND METHODS OF USE THEREOF NCOR2, NSD2, NCOR1 CA1 4590/4885CA2 4561/4885CA12 4129/4885
US-20230242506-A1 HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS TEAD1, TEAD2, TEAD4 CA1 4225/4885CA2 1815/4885CA12 3879/4885
US-20230167105-A1 BCL-2 PROTEIN INHIBITORS BCL2, BCL2L1, BCL2L2 CA1 2883/4885CA2 1299/4885CA12 3384/4885
US-20070249014-A1 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS PTMS, DNPEP, BTD CA1 969/4885CA2 2515/4885CA12 801/4885
US-20100261181-A1 LABELING AND DETECTION OF NUCLEIC ACIDS RNGTT, ADAR, ALKBH1 CA1 998/4885CA2 1593/4885CA12 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.