⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684937 | 0.80 | — | — | |
| SCHEMBL19326880 | 0.79 | PTGS1 (0.32) | — | |
| SCHEMBL861358 | 0.75 | KMT2A (0.31) | — | |
| SCHEMBL6417719 | 0.74 | — | — | |
| SCHEMBL45794 | 0.72 | PTGS1 (0.33) | — | |
| SCHEMBL1766181 | 0.72 | PTGS1 (0.36) | — | |
| SCHEMBL4974653 | 0.71 | PTGS1 (0.31) | — | |
| SCHEMBL23706381 | 0.70 | — | — | |
| SCHEMBL342325 | 0.69 | PSEN1 (0.31) | — | |
| SCHEMBL15969015 | 0.69 | PSEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089295-A2 | HOMOGENEOUS AND HETEROGENEOUS ASSAY METHODS USING NUCLEATION CENTERS AND NOVEL COVALENT CHEMISTRIES FOR THE RAPID MEASUREMENT OF PHOSPHORYLATION AND DE-PHOSPHORYLATION | CHROMAGEN, INC. (US) | 2004-10-21 | — | — | WO | claimed |
| US-20120329176-A1 | INDIRECTLY LABELLED ASSAY CONJUGATES AND METHODS OF PREPARING AND USING SAME | ABBOTT LABORATORIES (US) | 2012-12-27 | — | — | US | disclosed |
| US-7875708-B2 | Sialic acid derivatives | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2011-01-25 | — | — | US | disclosed |
| US-20100279432-A1 | INDIRECTLY LABELLED ASSAY CONJUGATES AND METHODS OF PREPARING AND USING SAME | ABBOTT LABORATORIES (US) | 2010-11-04 | — | — | US | disclosed |
| US-20090068635-A1 | INDIRECTLY LABELLED ASSAY CONJUGATES AND METHODS OF PREPARING AND USING SAME | ABBOTT LABORATORIES | 2009-03-12 | — | — | US | disclosed |
| US-20070282096-A1 | amine or hydrazide derivatives; for conjugation to proteins, drugs, drug delivery systems | OPKO PHARMACEUTICALS, LLC | 2007-12-06 | — | — | US | disclosed |
| WO-2004089295-A2 | HOMOGENEOUS AND HETEROGENEOUS ASSAY METHODS USING NUCLEATION CENTERS AND NOVEL COVALENT CHEMISTRIES FOR THE RAPID MEASUREMENT OF PHOSPHORYLATION AND DE-PHOSPHORYLATION | CHROMAGEN, INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| EP-1246854-B1 | PREPARATION OF POLYMERIZATION CATALYST AND RELATED POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-05-26 | — | — | EP | disclosed |
| US-6673735-B1 | REACTING TRIS(PERFLUOROPHENYL)BORANE WITH TRIMETHYLALUMINUM, THEN COMPLEXING THE INTERMEDIATES WITH DIMETHYLSILANE, BIS-(INDENYL-1-YL)ZIRCONIUM DIMETHYL, TO FORM COORDINATION CATALYST USED FOR ADDITION POLYMERIZATION | DOW GLOBAL TECHNOLOGIES INC. | 2004-01-06 | — | — | US | disclosed |