Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417719 | 0.87 | — | — | |
| SCHEMBL45794 | 0.84 | PTGS1 (0.33) | PTGER2 | |
| SCHEMBL19326880 | 0.78 | PTGS1 (0.32) | ALDH1A1 | |
| Bicarbonate SCHEMBL9228837 | 0.75 | HTR1A (0.34) | — | |
| SCHEMBL1019147 | 0.75 | — | — | |
| SCHEMBL14348230 | 0.74 | CPB2 (0.33) | — | |
| SCHEMBL181056 | 0.73 | HTR1A (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL5664409 | 0.73 | HTR1A (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL1766181 | 0.70 | PTGS1 (0.36) | ALDH1A1 | |
| SCHEMBL3800428 | 0.68 | PTGS1 (0.40) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433496-A1 | Tissue non-specific alkaline phosphatase inhibitors and uses thereof for treating vascular calcification | Burnham Institute for Medical Research (US) | 2012-03-28 | — | — | EP | disclosed |