Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA10 | Q9GZZ6 | 9/20 | 0.58 |
| ▸ | CHRNA9 | Q9UGM1 | 9/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085835 | 0.84 | AOC2 (0.59) | MEN1PMP22KMT2ASMN1; SMN2HIF1A | |
| SCHEMBL30476653 | 0.80 | HDAC6 (0.71) | MEN1PMP22KMT2ASMN1; SMN2HIF1A | |
| SCHEMBL5639759 | 0.80 | HDAC3 (0.68) | MEN1KMT2ASMN1; SMN2HDAC3HDAC8 | |
| Hydrochloric Acid SCHEMBL25319983 | 0.79 | HDAC6 (0.69) | MEN1PMP22KMT2ASMN1; SMN2HIF1A | |
| SCHEMBL7337653 | 0.79 | HDAC6 (0.69) | MEN1KMT2ASMN1; SMN2KDM4EALOX15 | |
| SCHEMBL12524169 | 0.78 | HDAC6 (0.61) | MEN1POLBKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL20456242 | 0.76 | CTSL (0.51) | MEN1PMP22KMT2ASMN1; SMN2HIF1A | |
| SCHEMBL20456264 | 0.75 | AOC2 (0.50) | MEN1POLBPMP22KMT2ASMN1; SMN2 | |
| SCHEMBL24202299 | 0.73 | HDAC6 (0.56) | MEN1POLBKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL4073782 | 0.73 | SMYD3 (0.48) | PMP22HIF1AKDM4ECYP3A4AOC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524347-A1 | USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | BASF SE (DE) | 2019-08-14 | — | — | EP | disclosed |
| EP-2271426-B1 | USE OF HYDRAZIDE COMPOUNDS AS OXIDATION CATALYSTS | BASF SE (DE) | 2019-02-20 | — | — | EP | disclosed |
| US-8791298-B2 | Use of metal hydrazide complex compounds as oxidation catalysts | BASF SE (DE) | 2014-07-29 | — | — | US | disclosed |
| US-20130281353-A1 | Use of Metal Hydrazide Complex Compounds as Oxidation Catalysts | BASF SE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-8492324-B2 | Use of metal hydrazide complex compounds as oxidation catalysts | BASF SE (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20110071066-A1 | USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | BASF SE (DE) | 2011-03-24 | — | — | US | disclosed |
| EP-2271426-A1 | USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | BASF SE (DE) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009124855-A1 | USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | BASF SE (DE) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071066-A1 | USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | SOD1, H1-4, H1-5 | CHRNA10 3034/4885CHRNA9 3739/4885CHRNA7 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.