Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627724 | 0.82 | HTR1A (0.51) | LTB4R2BDKRB1 | |
| SCHEMBL7867499 | 0.77 | BMP1 (0.47) | LTB4R2 | |
| SCHEMBL6624770 | 0.76 | SLC6A3 (0.46) | LTB4R2POLB | |
| SCHEMBL628630 | 0.76 | LOXL2 (0.50) | — | |
| SCHEMBL7862374 | 0.76 | HPGD (0.51) | LTB4R2 | |
| SCHEMBL630123 | 0.75 | SLC6A3 (0.43) | LTB4R2 | |
| SCHEMBL6774395 | 0.75 | SLC6A3 (0.44) | — | |
| SCHEMBL6625716 | 0.75 | SLC6A3 (0.43) | — | |
| SCHEMBL629652 | 0.75 | FNTA (0.44) | — | |
| SCHEMBL10193322 | 0.75 | FNTA (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |