Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130104 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1464202 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10193067 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29500256 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL472429 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL292958 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL258422 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13050357 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7089968 | 0.98 | ALDH1A1 (0.52) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| P-Xylene SCHEMBL5424500 | 0.98 | ALDH1A1 (0.52) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2868659-B1 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-04 | — | — | EP | claimed |
| US-9181217-B2 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-11-10 | — | — | US | claimed |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-06-04 | — | — | US | claimed |
| EP-2868659-A1 | Method for producing optically active naphthalene compound | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-05-06 | — | — | EP | claimed |
| EP-2749558-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2014-07-02 | — | — | EP | claimed |
| US-20260125380-A1 | PRMT5 INHIBITORS AND METHODS OF USE | SHANGHAI APEIRON THERAPEUTICS COMPANY LIMITED (CN) | 2026-05-07 | — | — | US | disclosed |
| EP-4592289-A1 | NOVEL PRMT5 INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-07-30 | — | — | EP | disclosed |
| US-20250051331-A1 | PRMT5 INHIBITORS AND METHODS OF USE | SHANGHAI APEIRON THERAPEUTICS COMPANY LIMITED (CN) | 2025-02-13 | — | — | US | disclosed |
| US-12173002-B2 | PRMT5 inhibitors and methods of use | SHANGHAI APEIRON THERAPEUTICS COMPANY LIMITED (CN) | 2024-12-24 | — | — | US | disclosed |
| US-20240294528-A1 | PRMT5 INHIBITORS AND METHODS OF USE | SHANGHAI APEIRON THERAPEUTICS COMPANY LIMITED (CN) | 2024-09-05 | — | — | US | disclosed |
| US-9382280-B2 | Diamine compound and metal complexes, and method for producing optically active compounds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2868659-B1 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-04 | — | — | EP | disclosed |
| EP-1944291-B1 | Optically active cyclic alcohol compound and method for producing same | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-06-13 | — | — | EP | disclosed |
| EP-2371820-A1 | Optically active cyclic alcohol compound and method for preparing the same | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20110196157-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION | 2011-08-11 | — | — | US | disclosed |
| US-20100152451-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100048537-A1 | HETEROARYL DERIVATIVES | NIPPON SHINYAKU CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2141168-A1 | HETEROARYL DERIVATIVES | Nippon Shinyaku Co., Ltd. (JP) | 2010-01-06 | — | — | EP | disclosed |
| EP-1944291-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-16 | — | — | EP | disclosed |
| JP-2000016954-A | PRODUCTION OF OPTICALLY ACTIVE 1,2-DIOLS | MITSUBISHI CHEMICALS CORP | 2000-01-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12173002-B2 | PRMT5 inhibitors and methods of use | PRMT5, PRMT1, PRMT7 | ALDH1A1 3578/4885NPSR1 3874/4885SLC1A3 1336/4885 |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | HRH1, HRH4, RB1 | ALDH1A1 343/4885NPSR1 595/4885SLC1A3 4437/4885 |
| US-20250051331-A1 | PRMT5 INHIBITORS AND METHODS OF USE | PRMT5, PRMT1, PRMT7 | ALDH1A1 3523/4885NPSR1 3985/4885SLC1A3 872/4885 |
| US-20110196157-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | ADH1C, ADH1A, ADH5 | ALDH1A1 25/4885NPSR1 3303/4885SLC1A3 3110/4885 |
| US-20100152451-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | ADH1C, ADH1A, ADH5 | ALDH1A1 25/4885NPSR1 3303/4885SLC1A3 3110/4885 |
| US-20100048537-A1 | HETEROARYL DERIVATIVES | OPRD1, OPRM1, OPRK1 | ALDH1A1 66/4885NPSR1 13/4885SLC1A3 454/4885 |
| US-20260125380-A1 | PRMT5 INHIBITORS AND METHODS OF USE | PRMT1, PRMT5, PRMT6 | ALDH1A1 4399/4885NPSR1 3839/4885SLC1A3 2197/4885 |
| US-20240294528-A1 | PRMT5 INHIBITORS AND METHODS OF USE | PRMT5, PRMT1, PRMT3 | ALDH1A1 3659/4885NPSR1 3471/4885SLC1A3 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.