Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500256 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10193067 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13050357 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL472429 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL258422 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL292958 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2239236 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL130104 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1464202 | 0.98 | ALDH1A1 (0.53) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 | |
| P-Xylene SCHEMBL5424500 | 0.97 | ALDH1A1 (0.52) | ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-12-04 | — | — | US | disclosed |
| EP-1209150-A1 | PROCESSES FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ADH1A, ADH1C, OXER1 | ALDH1A1 80/4885NPSR1 755/4885SLC1A3 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.