Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898070 | 0.82 | FAAH (0.42) | FAAHMAPTTHRBTP53LMNA | |
| SCHEMBL8276503 | 0.82 | FAAH (0.42) | FAAHMAPTTHRBTP53LMNA | |
| SCHEMBL25459993 | 0.78 | FAAH (0.43) | FAAHMAPTTHRBTP53LMNA | |
| SCHEMBL9688656 | 0.77 | MAPT (0.68) | FAAHMAPTTHRBTP53LMNA | |
| SCHEMBL7319885 | 0.77 | LMNA (0.46) | FAAHMAPTTHRBTP53LMNA | |
| SCHEMBL7317657 | 0.77 | LMNA (0.62) | FAAHMAPTTHRBTP53LMNA | |
| SCHEMBL24796482 | 0.76 | LMNA (0.45) | FAAHMAPTTHRBTP53LMNA | |
| SCHEMBL6989194 | 0.75 | FAAH (0.51) | FAAHMAPTLMNAHTR3AAHR | |
| SCHEMBL19118698 | 0.73 | CA2 (0.49) | FAAHMAPTTHRBTP53LMNA | |
| Hydrochloric Acid SCHEMBL11786890 | 0.72 | MAPT (0.42) | FAAHMAPTTHRBTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2422781-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2422780-A1 | Resistance-repellent retroviral protease inhibitors | Sequoia Pharmaceuticals, Inc. (US) | 2012-02-29 | — | — | EP | disclosed |