Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10194735 | 0.87 | IDO1 (0.37) | GPR119WDR5HPGDSMN1; SMN2GAA | |
| SCHEMBL17850414 | 0.81 | HPGD (0.40) | WDR5HPGDSMN1; SMN2GAANPC1 | |
| SCHEMBL10195751 | 0.76 | ESRRA (0.40) | GPR119CA1CA2CA9CA12 | |
| SCHEMBL9952570 | 0.71 | GRM1 (0.40) | GPR119HPGDSMN1; SMN2GAANPC1 | |
| SCHEMBL10194916 | 0.68 | IDO1 (0.42) | WDR5HPGDSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL24372818 | 0.68 | HPGD (0.59) | HPGDSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL1284776 | 0.68 | HPGD (0.62) | HPGDSMN1; SMN2NPC1ALDH1A1KMT2A | |
| SCHEMBL18379003 | 0.68 | HSD17B10 (0.55) | HPGDSMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL27400423 | 0.67 | ALDH1A1 (0.55) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL10194740 | 0.67 | GAA (0.39) | SMN1; SMN2GAALMNAKDM4EIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084704-A1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO S.A. (CH) | 2012-06-28 | — | — | WO | disclosed |