Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | UBE2M | P61081 | 1/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10197819 | 0.89 | ALDH1A1 (0.60) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12558144 | 0.89 | NPC1 (0.58) | MAPTKDM4ENPC1TSHRRAB9A | |
| SCHEMBL24746313 | 0.86 | NPC1 (0.62) | MAPTKDM4ENPC1TSHRRAB9A | |
| SCHEMBL15886244 | 0.80 | NAMPT (0.56) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12764173 | 0.78 | MEN1 (0.69) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL15886277 | 0.77 | NPC1 (0.57) | KDM4ENPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL24354873 | 0.76 | PKM (0.60) | MAPTKDM4ENPC1TSHRRAB9A | |
| SCHEMBL17029179 | 0.76 | NPC1 (0.60) | MAPTKDM4ENPC1TSHRRAB9A | |
| SCHEMBL12561534 | 0.75 | NPC1 (0.49) | MAPTKDM4ENPC1TSHRRAB9A | |
| SCHEMBL12764175 | 0.75 | RAB9A (0.74) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006104-A2 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | Academia Sinica, Taiwan (TW) | 2012-01-12 | — | — | WO | disclosed |