Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | IL1B | P01584 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18508855 | 0.82 | HTR2C (0.44) | CDK2HTR2CHTR2BHTR2AGPR84 | |
| SCHEMBL8290971 | 0.82 | HTR2C (0.39) | CDK2HTR2CHTR2BHTR2AP2RX7 | |
| SCHEMBL3833273 | 0.76 | CDK2 (0.47) | CDK2HTR2CHTR2BHTR2AMCL1 | |
| SCHEMBL1093107 | 0.75 | GPR84 (0.42) | CDK2HTR2CHTR2BHTR2AP2RX7 | |
| SCHEMBL10197977 | 0.75 | HTR2C (0.68) | CDK2HTR2CHTR2BHTR2AGPR84 | |
| SCHEMBL10259878 | 0.75 | HTR2A (0.41) | CDK2HTR2CHTR2BHTR2AGPR84 | |
| Trimethylammonium SCHEMBL5399049 | 0.74 | HTR2C (0.47) | CDK2HTR2CHTR2BHTR2AGPR84 | |
| Iodide SCHEMBL5399054 | 0.74 | CHRNB2 (0.41) | CDK2HTR2CHTR2BHTR2AGPR84 | |
| SCHEMBL18509533 | 0.74 | MCL1 (0.51) | CDK2HTR2CHTR2BHTR2AMCL1 | |
| SCHEMBL14278470 | 0.73 | SLC5A2 (0.43) | CDK2HTR2CHTR2BHTR2AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546358-B2 | Method of treating asthma | JANSSEN PHARMACEUTICA NV (BE) | 2013-10-01 | — | — | US | disclosed |
| US-20120022022-A1 | NOVEL INHIBITORS OF CHYMASE | HAWKINS MICHAEL J (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022022-A1 | NOVEL INHIBITORS OF CHYMASE | CMA1, SERPINB1, TPSAB1 | CDK2 827/4885HTR2C 3442/4885HTR2B 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.