SCHEMBL1019935

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL943580	0.89	MEN1 (0.60)	PHGDHMAPTGAAMEN1KMT2A
	SCHEMBL942657	0.87	PHGDH (0.53)	PHGDHMAPTGAAMEN1KMT2A
	SCHEMBL943005	0.84	PHGDH (0.50)	PHGDHMAPTGAAMEN1KMT2A
	SCHEMBL942805	0.82	SIRT6 (0.56)	MAPTMEN1KMT2AALDH1A1LMNA
	SCHEMBL944124	0.82	PHGDH (0.46)	PHGDHMAPTGAAMEN1KMT2A
	SCHEMBL1991994	0.81	PHGDH (0.48)	PHGDHMAPTGAAMEN1KMT2A
	SCHEMBL942632	0.81	PHGDH (0.48)	PHGDHMAPTGAAMEN1KMT2A
	SCHEMBL1991990	0.81	PHGDH (0.48)	PHGDHMAPTGAAMEN1KMT2A
	SCHEMBL943495	0.79	LMNA (0.58)	MAPTMEN1KMT2AALDH1A1LMNA
	SCHEMBL943333	0.78	MAPT (0.56)	PHGDHMAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.