Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TPMT | P51580 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935201 | 0.87 | EGFR (0.51) | EGFRTSHRTPMTCA12CA1 | |
| SCHEMBL28183665 | 0.86 | MGLL (0.52) | EGFRCA12CA1CA2CA7 | |
| SCHEMBL31156176 | 0.86 | MGLL (0.52) | EGFRCA12CA1CA2CA7 | |
| SCHEMBL3480035 | 0.85 | TSHR (0.63) | EGFRTSHRTPMTCA12CA1 | |
| SCHEMBL16382251 | 0.84 | ESR1 (0.43) | EGFRTSHRCA12CA1CA2 | |
| SCHEMBL4948306 | 0.83 | TSHR (0.66) | TSHRTPMTCA12CA1CA2 | |
| SCHEMBL3480458 | 0.83 | TSHR (0.61) | EGFRTSHRTPMTCA12CA1 | |
| SCHEMBL6568030 | 0.82 | TSHR (0.73) | EGFRTSHRTPMTCA12CA1 | |
| SCHEMBL3046092 | 0.82 | CA12 (0.71) | EGFRTSHRTPMTCA12CA1 | |
| SCHEMBL30010958 | 0.81 | TPMT (0.69) | TSHRTPMTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505979-B2 | Polymerizable liquid crystal compounds, liquid crystal composition comprising the compounds, and optical film comprising the composition | LG CHEM, LTD. (KR) | 2016-11-29 | — | — | US | disclosed |
| US-9416317-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and optical anisotropic body | LG CHEM, LTD. (KR) | 2016-08-16 | — | — | US | disclosed |
| US-9416317-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and optical anisotropic body | LG CHEM, LTD. (KR) | 2016-08-16 | — | — | US | disclosed |
| US-20160200977-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL COMPOSITION COMPRISING THE COMPOUNDS, AND OPTICAL FILM COMPRISING THE COMPOSITION (As Amended) | LG CHEM, LTD. (KR) | 2016-07-14 | — | — | US | disclosed |
| US-20160024385-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICAL ANISOTROPIC BODY | LG CHEM, LTD. (KP) | 2016-01-28 | — | — | US | disclosed |
| US-20160024385-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICAL ANISOTROPIC BODY | LG CHEM, LTD. (KP) | 2016-01-28 | — | — | US | disclosed |
| US-9206355-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and optically anisotropic body | LG CHEM, LTD. (KR) | 2015-12-08 | — | — | US | disclosed |
| US-9206355-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and optically anisotropic body | LG CHEM, LTD. (KR) | 2015-12-08 | — | — | US | disclosed |
| US-20150115199-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICALLY ANISOTROPIC BODY | LG CHEM, LTD. (KR) | 2015-04-30 | — | — | US | disclosed |
| US-20150115199-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICALLY ANISOTROPIC BODY | LG CHEM, LTD. (KR) | 2015-04-30 | — | — | US | disclosed |
| WO-2015046825-A2 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, AND LIQUID CRYSTAL COMPOSITION AND OPTICAL FILM COMPRISING SAME | 주식회사 엘지화학 | 2015-04-02 | — | — | WO | disclosed |
| EP-2824162-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, AND OPTICAL ANISOTROPIC BODY | LG Chem, Ltd. (KR) | 2015-01-14 | — | — | EP | disclosed |
| US-8569336-B2 | Compounds for the treatment of inflammatory disorders | TONG LING (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569336-B2 | Compounds for the treatment of inflammatory disorders | TONG LING (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120015926-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TONG LING (US) | 2012-01-19 | — | — | US | disclosed |
| US-20120015926-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TONG LING (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015926-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TNF, ADAMTS1, ADAMTS7 | EGFR 1224/4885TSHR 3563/4885TPMT 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.