Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201174 | 0.90 | HCRTR1 (0.43) | HCRTR1HCRTR2CHEK2 | |
| SCHEMBL10201488 | 0.89 | L3MBTL1 (0.40) | GABRG2GABRB3GABRA5GABRA4GABRA1 | |
| SCHEMBL203367 | 0.87 | HCRTR1 (0.46) | UCHL1GABRG2GABRB3GABRA5GABRA4 | |
| SCHEMBL2708720 | 0.87 | HCRTR1 (0.46) | UCHL1GABRG2GABRB3GABRA5GABRA4 | |
| SCHEMBL12373624 | 0.87 | GABRA5 (0.37) | UCHL1GABRG2GABRB3GABRA5GABRA4 | |
| SCHEMBL12373606 | 0.86 | GABRA5 (0.38) | UCHL1GABRG2GABRB3GABRA5GABRA4 | |
| SCHEMBL12373556 | 0.85 | UCHL1 (0.43) | UCHL1GABRG2GABRB3GABRA5GABRA4 | |
| SCHEMBL883264 | 0.85 | CYP3A4 (0.42) | HCRTR1HCRTR2CHEK2 | |
| SCHEMBL10202473 | 0.84 | PTGES (0.40) | L3MBTL1HCRTR1HCRTR2PTGES | |
| SCHEMBL6125920 | 0.84 | HCRTR1 (0.44) | UCHL1ALDH1A1L3MBTL1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |