SCHEMBL1020197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1885707	0.93	POLB (0.48)	POLBESR2CA2SMN1; SMN2HTR6
	SCHEMBL1887026	0.90	CA2 (0.39)	POLBESR2CA2SMN1; SMN2ALDH1A1
	SCHEMBL1019793	0.89	CA2 (0.43)	POLBESR2CA2ALDH1A1HTR6
	SCHEMBL1081607	0.88	CA2 (0.40)	POLBESR2CA2ALDH1A1HTR6
	SCHEMBL1019903	0.88	CA2 (0.40)	POLBESR2CA2ALDH1A1HTR6
	SCHEMBL1082579	0.87	CA2 (0.42)	POLBESR2CA2SMN1; SMN2ALDH1A1
	SCHEMBL1887040	0.86	ADRA1D (0.43)	CA2ALDH1A1ADRA1DADRA1AADRA1B
	SCHEMBL1885285	0.84	HTR6 (0.50)	CA2ALDH1A1HTR6ADRA1DADRA1A
	SCHEMBL1018443	0.83	CA2 (0.40)	POLBESR2CA2ALDH1A1HTR6
	SCHEMBL1884497	0.83	CA2 (0.40)	CA2HTR6ADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.