Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	MAOA known ✓	P21397	3/20	0.60

▸	SCN1A known ✓	P35498	3/20	0.58

▸	SCN2A known ✓	Q99250	3/20	0.58

▸	SCN3A known ✓	Q9NY46	3/20	0.58

▸	SCN7A known ✓	Q01118	1/20	0.53

▸	SLC6A3 known ✓	Q01959	1/20	0.53

▸	SCN5A known ✓	Q14524	1/20	0.53

▸	SCN9A known ✓	Q15858	1/20	0.53

▸	SCN8A known ✓	Q9UQD0	1/20	0.53

▸	HRH3	Q9Y5N1	3/20	0.60

▸	TSHR	P16473	2/20	0.60

▸	CYP2D6	P10635	2/20	0.60

▸	HTR3A	P46098	1/20	0.60

▸	BLM	P54132	2/20	0.59

▸	NPSR1	Q6W5P4	1/20	0.59

▸	LMNA	P02545	5/20	0.58

▸	ATM	Q13315	1/20	0.54

▸	L3MBTL1	Q9Y468	1/20	0.54

▸	CYP1A2	P05177	2/20	0.53

▸	KCNH2	Q12809	2/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Iodide SCHEMBL1022754	0.93	HRH3 (0.65)	MAOAHRH3TSHRCYP2D6HTR3A
Bicarbonate SCHEMBL1021919	0.92	HRH3 (0.63)	MAOAHRH3TSHRCYP2D6HTR3A
SCHEMBL10645561	0.83	HPGD (0.68)	MAOAHRH3TSHRCYP2D6HTR3A
Procaine SCHEMBL6537522	0.82	CYP2D6 (0.89)	MAOAHRH3TSHRCYP2D6HTR3A
SCHEMBL4295410	0.82	HRH3 (0.68)	MAOAHRH3TSHRCYP2D6HTR3A
SCHEMBL94128	0.82	HRH3 (0.68)	MAOAHRH3TSHRCYP2D6HTR3A
P-Butylaminobenzoyldiethylaminoethyl SCHEMBL503019	0.82	SCN1A (0.79)	MAOAHRH3TSHRCYP2D6HTR3A
SCHEMBL4916550	0.82	HRH3 (0.60)	MAOAHRH3TSHRCYP2D6HTR3A
SCHEMBL6677	0.81	HRH3 (0.67)	MAOAHRH3TSHRCYP2D6HTR3A
SCHEMBL9576578	0.81	HRH3 (0.71)	MAOAHRH3TSHRCYP2D6HTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1776333-B1	AMMONIUM SALTS AND AMMONIUM SALT/MINERAL SALT CLATHRATE COMPOUNDS FOR USE AS VEHICLE AND EFFECTIVE FORM FOR PHARMACO-MEDICAL APPLICATIONS AND FOR USE AS PHASE TRANSFER AGENTS FOR CHEMICAL APPLICATIONS	KASCH HELMUT (DE)	2011-01-12	—	—	EP	disclosed
EP-1776333-A2	AMMONIUM SALTS AND AMMONIUM SALT/MINERAL SALT CLATHRATE COMPOUNDS FOR USE AS VEHICLE AND EFFECTIVE FORM FOR PHARMACO-MEDICAL APPLICATIONS AND FOR USE AS PHASE TRANSFER AGENTS FOR CHEMICAL APPLICATIONS	Kasch, Helmut (DE)	2007-04-25	—	—	EP	disclosed
WO-2006007835-A2	AMMONIUM SALTS AND AMMONIUM SALT/MINERAL SALT CLATHRATE COMPOUNDS FOR USE AS VEHICLE AND EFFECTIVE FORM FOR PHARMACO-MEDICAL APPLICATIONS AND FOR USE AS PHASE TRANSFER AGENTS FOR CHEMICAL APPLICATIONS	KASCH HELMUT (DE)	2006-01-26	—	—	WO	disclosed