Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.43 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737050 | 0.85 | CHRNA7 (0.46) | EGFRSRCKDRLMNAHTT | |
| SCHEMBL2737111 | 0.85 | MAPT (0.49) | EGFRSRCKDRKMT2ALMNA | |
| SCHEMBL2737123 | 0.85 | HPGD (0.57) | SRCMEN1KMT2ALMNAMAPT | |
| SCHEMBL13594234 | 0.85 | HDAC1 (0.48) | EGFRSRCKDRGAAMAPT | |
| SCHEMBL12309493 | 0.84 | KDM4E (0.53) | KDM4E | |
| SCHEMBL2737105 | 0.84 | CA12 (0.51) | EGFRSRCKDRMEN1KMT2A | |
| SCHEMBL2736916 | 0.83 | GABRA1 (0.46) | EGFRSRCKDRMEN1KMT2A | |
| SCHEMBL2736511 | 0.82 | HPGD (0.47) | EGFRSRCKDRKMT2ALMNA | |
| SCHEMBL2736546 | 0.81 | LMNA (0.44) | EGFRSRCKDRLMNAMAPT | |
| SCHEMBL10208262 | 0.81 | HPGD (0.46) | EGFRSRCKDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |