Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12309515 | 0.86 | KDM4E (0.48) | — | |
| SCHEMBL2736546 | 0.86 | LMNA (0.44) | HPGDALDH1A1MAPTHTTRAB9A | |
| SCHEMBL2737111 | 0.85 | MAPT (0.49) | HPGDKMT2AALDH1A1MAPTHTT | |
| SCHEMBL2736769 | 0.84 | PTGER4 (0.41) | HPGDALDH1A1MAPTHTTRAB9A | |
| SCHEMBL10207671 | 0.81 | EGFR (0.48) | MEN1KMT2AMAPTHTTEGFR | |
| SCHEMBL2736916 | 0.81 | GABRA1 (0.46) | MEN1KMT2ARAB9AEGFRSRC | |
| SCHEMBL2736511 | 0.79 | HPGD (0.47) | HPGDKMT2AALDH1A1MAPTHTT | |
| SCHEMBL2737105 | 0.78 | CA12 (0.51) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12309620 | 0.74 | — | — | |
| SCHEMBL13594234 | 0.73 | HDAC1 (0.48) | ALDH1A1MAPTEGFRSRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |