⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14490563 | 0.80 | KMT2A (0.31) | — | |
| SCHEMBL10268936 | 0.79 | LRRK2 (0.31) | — | |
| SCHEMBL10212016 | 0.77 | ACACB (0.35) | — | |
| SCHEMBL15177322 | 0.76 | ROCK2 (0.31) | — | |
| SCHEMBL13071297 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL10211987 | 0.71 | TGM2 (0.34) | — | |
| SCHEMBL13244221 | 0.71 | KMT2A (0.30) | — | |
| SCHEMBL10211998 | 0.68 | TGM2 (0.32) | — | |
| SCHEMBL10267999 | 0.68 | LRRK2 (0.34) | — | |
| SCHEMBL13096263 | 0.68 | THRB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507537-B2 | Trifluromethoxyphenyl-substituted tetramic acid derivatives pesticides and/or herbicides | BAYER CROPSCIENCE AG (DE) | 2013-08-13 | — | — | US | disclosed |
| US-20120015807-A1 | Trifluromethoxyphenyl-Substituted Tetramic Acid Derivatives Pesticides and/or Herbicides | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20120015807-A1 | Trifluromethoxyphenyl-Substituted Tetramic Acid Derivatives Pesticides and/or Herbicides | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | US | disclosed |
| EP-2121597-B1 | TRIFLUOROMETHOXYPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PESTICIDES AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-21 | — | — | EP | disclosed |
| WO-2008067873-A1 | TRIFLUOROMETHOXYPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PESTICIDES AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-06-12 | — | — | WO | disclosed |