Ethylene Glycol

Ethylene Glycol

SCHEMBL1021415

Cc1cc(C)c(C)cc1C.OCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
MAPK1 P28482 2/20 0.42
CYP3A4 P08684 1/20 0.42
ALDH1A1 P00352 4/20 0.38
PGK1 P00558 2/20 0.36
PGK2 P07205 2/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 3/20 0.33
SHBG P04278 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL21899428 0.79 CYP3A4 (0.50) TSHRMAPK1CYP3A4ALDH1A1PGK1
SCHEMBL8109982 0.78 TSHR (0.57) TSHRMAPK1CYP3A4ALDH1A1CA1
SCHEMBL39444 0.78 TSHR (0.57) TSHRMAPK1CYP3A4ALDH1A1CA1
Ethylene Glycol SCHEMBL3080883 0.77 ALDH1A1 (0.53) TSHRALDH1A1PGK1PGK2CA2
SCHEMBL28636923 0.76 NPSR1 (0.48) TSHRMAPK1CYP3A4ALDH1A1PGK1
SCHEMBL27965601 0.76 TSHR (0.36) TSHRMAPK1CYP3A4ALDH1A1PGK1
SCHEMBL394846 0.74 SHBG (0.48) TSHRMAPK1CYP3A4ALDH1A1PGK1
Ethylene Glycol SCHEMBL7203024 0.74 CD44 (0.48) TSHRCYP3A4ALDH1A1CA1CA2
SCHEMBL5180999 0.74 TSHR (0.53) TSHRMAPK1CYP3A4ALDH1A1CA1
SCHEMBL31498545 0.74 TSHR (0.53) TSHRMAPK1CYP3A4ALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2137227-B1 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE SABIC INNOVATIVE PLASTICS IP (NL) 2011-09-28 EP disclosed
EP-2137228-B1 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE SABIC INNOVATIVE PLASTICS IP (NL) 2011-01-12 EP disclosed
EP-2137228-A2 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE Sabic Innovative Plastics IP B.V. (NL) 2009-12-30 EP disclosed
EP-2137227-A2 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE Sabic Innovative Plastics IP B.V. (NL) 2009-12-30 EP disclosed
WO-2009044283-A2 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE SABIC INNOVATIVE PLASTICS IP B.V. (US) 2009-04-09 WO disclosed
WO-2009037574-A2 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE SABIC INNOVATIVE PLASTICS IP B.V. (US) 2009-03-26 WO disclosed
US-20080242784-A1 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE CITIBANK, N.A., AS COLLATERAL AGENT 2008-10-02 US disclosed
US-20080242783-A1 POLYESTER COMPOSITIONS HAVING IMPROVED HEAT RESISTANCE CITIBANK, N.A., AS COLLATERAL AGENT 2008-10-02 US disclosed
US-5192471-A PROCESS FOR PREPARING CARBON/CARBON COMPOSITE NIPPON OIL COMPANY, LIMITED (JP) 1993-03-09 US disclosed
US-5186873-A PROCESS FOR PREPARING CARBON/CARBON COMPOSITE NIPPON OIL COMPANY, LIMITED (JP) 1993-02-16 US disclosed
EP-0457510-A2 Process for preparing carbon/carbon composite NIPPON OIL COMPANY, LIMITED (JP) 1991-11-21 EP disclosed
EP-0457509-A2 Process for preparing carbon/carbon composite NIPPON OIL COMPANY, LIMITED (JP) 1991-11-21 EP disclosed