Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021631 | 1.00 | TPH1 (0.51) | TPH1ALDH1A1LMNASCN9ASMN1; SMN2 | |
| SCHEMBL21540448 | 0.93 | ALDH1A1 (0.48) | TPH1ALDH1A1LDHAITGB1ITGA4 | |
| SCHEMBL4315119 | 0.89 | TPH1 (0.49) | TPH1LDHA | |
| SCHEMBL21519755 | 0.89 | TPH1 (0.49) | TPH1LDHA | |
| SCHEMBL919730 | 0.88 | TPH1 (0.52) | TPH1ALDH1A1LMNASCN9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL919728 | 0.87 | TPH1 (0.53) | TPH1ALDH1A1LMNASCN9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27504082 | 0.87 | TPH1 (0.53) | TPH1ALDH1A1LMNASCN9ASMN1; SMN2 | |
| SCHEMBL918869 | 0.86 | TPH1 (0.51) | TPH1ALDH1A1LMNASCN9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL918867 | 0.85 | TPH1 (0.52) | TPH1ALDH1A1LMNASCN9ASMN1; SMN2 | |
| SCHEMBL3835529 | 0.83 | TPH1 (0.45) | TPH1ALDH1A1LMNASCN9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478619-B1 | A PROCESS FOR PREPARING A PHENYLALANINE DERIVATIVE AND INTERMEDIATES THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-01-12 | — | — | EP | disclosed |
| US-7476758-B2 | Process for preparing a phenylalanine derivative and intermediates thereof | MITSUBISHI TANBE PHARMA CORPORATION (JP) | 2009-01-13 | — | — | US | disclosed |
| US-20050165107-A1 | Process for preparing a phenylalanine derivative and intermediates thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165107-A1 | Process for preparing a phenylalanine derivative and intermediates thereof | ITGB4, ITGA4, ITGA5 | TPH1 2434/4885ALDH1A1 477/4885LMNA 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.