Sugi Predict

Sugi Predict / Compounds / SCHEMBL10225916

SCHEMBL10225916

SCHEMBL10225916

CC(C)c1ccc2[nH]c3ccc(-c4cccc5c4sc4ccccc45)cc3c2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.52
▸ KIF11 P52732 2/20 0.46
▸ PARP14 Q460N5 1/20 0.38
▸ PRKDC P78527 2/20 0.38
▸ MAPT P10636 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ KDM4E B2RXH2 2/20 0.36
▸ TNKS O95271 2/20 0.35
▸ TNKS2 Q9H2K2 2/20 0.35
▸ PIM1 P11309 2/20 0.35
▸ PIM2 Q9P1W9 2/20 0.35
▸ PAX8 Q06710 1/20 0.34
▸ NOD2 Q9HC29 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ CCNB2 O95067 1/20 0.34
▸ CDK1 P06493 1/20 0.34
▸ CCNB1 P14635 1/20 0.34
▸ CCNB3 Q8WWL7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL787967 0.88 ALOX5 (0.64) ALOX5KIF11PARP14PRKDCMAPT
SCHEMBL31664386 0.86 ALOX5 (0.61) ALOX5KIF11PARP14PRKDCMAPT
SCHEMBL29720834 0.86 ALOX5 (0.61) ALOX5KIF11PARP14PRKDCMAPT
SCHEMBL457901 0.86 ALOX5 (0.61) ALOX5KIF11PARP14PRKDCMAPT
SCHEMBL26415753 0.84 ALOX5 (0.56) ALOX5PARP14PRKDCMAPTRAB9A
SCHEMBL789531 0.84 ALOX5 (0.56) ALOX5KIF11PARP14PRKDCMAPT
SCHEMBL10227108 0.83 KIF11 (0.50) ALOX5KIF11MAPTRAB9AMEN1
SCHEMBL10225928 0.83 ALOX5 (0.58) ALOX5PARP14PRKDCMAPTRAB9A
SCHEMBL789548 0.83 ALOX5 (0.58) ALOX5PARP14PRKDCMAPTRAB9A
SCHEMBL10225922 0.83 ALOX5 (0.58) ALOX5PARP14PRKDCMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 — — US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 — — US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 — — US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885KIF11 1085/4885PARP14 3228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.