Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92528 | 0.89 | HCRTR2 (0.37) | ALDH1A1MEN1KMT2ATSHRHCRTR2 | |
| SCHEMBL92529 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ATSHRHCRTR2 | |
| SCHEMBL92568 | 0.87 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ATSHRHCRTR2 | |
| SCHEMBL10225943 | 0.84 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ATSHRHCRTR2 | |
| SCHEMBL92569 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ATSHRHCRTR2 | |
| SCHEMBL13698642 | 0.82 | MEN1 (0.35) | ALDH1A1MEN1KMT2ATSHRHCRTR2 | |
| SCHEMBL85286 | 0.82 | MAPT (0.36) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL14254485 | 0.78 | MEN1 (0.39) | ALDH1A1MEN1KMT2ATSHRHCRTR2 | |
| SCHEMBL13437496 | 0.78 | MEN1 (0.39) | ALDH1A1MEN1KMT2ATSHRHCRTR2 | |
| SCHEMBL14592647 | 0.75 | HCRTR2 (0.43) | ALDH1A1MEN1KMT2ATSHRHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157437-A1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157437-A1 | VLA-4 INHIBITORY DRUG | VCAM1, ITGB4, ITGA4 | ALDH1A1 216/4885MEN1 4254/4885KMT2A 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.