SCHEMBL10227201

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1638395	0.94	APP (0.50)	APPCA12CA1CA2CA4
	SCHEMBL21192815	0.87	KDM4E (0.42)	APPCA12CA1CA2CA4
	SCHEMBL20321535	0.85	HTR7 (0.45)	APPCA12CA1CA2CA4
	SCHEMBL11865786	0.84	MAPK14 (0.52)	APPCA12CA1CA2CA4
	SCHEMBL31070104	0.83	MAP2 (0.48)	APPHTR7ALDH1A1HPGDSMN1; SMN2
	SCHEMBL21204291	0.83	KDM4E (0.42)	APPCA12CA1CA2CA4
	SCHEMBL21192807	0.83	MAP2 (0.48)	APPHTR7ALDH1A1HPGDSMN1; SMN2
	SCHEMBL20321536	0.83	APP (0.42)	APPCA12CA1CA2CA4
	SCHEMBL20321534	0.83	ALDH1A1 (0.47)	APPCA12CA1CA2CA4
	SCHEMBL22285911	0.83	CA12 (0.52)	APPCA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.