Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6849471 | 0.83 | KMT2A (0.53) | ALDH1A1TSHRMAPTSMN1; SMN2HPGD | |
| SCHEMBL4625960 | 0.81 | KMT2A (0.54) | ALDH1A1TSHRMAPTSMN1; SMN2HPGD | |
| SCHEMBL4624305 | 0.77 | ALDH1A1 (0.45) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL2240089 | 0.75 | HTT (0.63) | HTTALDH1A1CA1CA2CA12 | |
| Iodide SCHEMBL2530877 | 0.75 | QDPR (0.34) | TSHRHPGD | |
| Hydrochloric Acid SCHEMBL6386993 | 0.74 | HTT (0.48) | HTTALDH1A1CA1CA2CA12 | |
| SCHEMBL14684755 | 0.74 | CYP1A2 (0.48) | HTTALDH1A1CA1CA2CA12 | |
| SCHEMBL6849554 | 0.74 | KMT2A (0.46) | ALDH1A1CA12CA9TSHRMAPT | |
| Iodide SCHEMBL3568331 | 0.73 | TSHR (0.56) | ALDH1A1CA1CA2CA12CA7 | |
| Hydrochloric Acid SCHEMBL3854519 | 0.72 | ALDH1A1 (0.61) | HTTALDH1A1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8384068-B2 | Use of acridine derivatives as matrix materials and/or electron blockers in OLEDs | BASF SE (DE) | 2013-02-26 | — | — | US | disclosed |
| EP-2195868-B1 | USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR AN ELECTRON BLOCKER IN OLEDS | BASF SE (DE) | 2013-01-02 | — | — | EP | disclosed |
| US-7989091-B2 | Silanes containing phenothiazine-S-oxide or phenothiazine-S,S-dioxide groups and the use thereof in OLEDs | BASF SE (DE) | 2011-08-02 | — | — | US | disclosed |
| EP-2150556-B1 | SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS | BASF SE (DE) | 2011-01-12 | — | — | EP | disclosed |
| US-20100219406-A1 | USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS | BASF SE (DE) | 2010-09-02 | — | — | US | disclosed |
| US-20100187980-A1 | SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS | BASF SE (DE) | 2010-07-29 | — | — | US | disclosed |
| EP-2195868-A1 | USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR AN ELECTRON BLOCKER IN OLEDS | Basf Se (DE) | 2010-06-16 | — | — | EP | disclosed |
| EP-2150556-A1 | SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS | BASF SE (DE) | 2010-02-10 | — | — | EP | disclosed |
| WO-2009047147-A1 | USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR AN ELECTRON BLOCKER IN OLEDS | BASF SE (DE) | 2009-04-16 | — | — | WO | disclosed |
| WO-2008132085-A1 | SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS | BASF SE (DE) | 2008-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100187980-A1 | SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS | OPRD1, PPID, PLOD2 | HTT 137/4885ALDH1A1 980/4885CA1 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.