Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15477537 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15477542 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL31679623 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9805470 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9805448 | 0.98 | TSHR (0.58) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL632865 | 0.93 | TSHR (0.55) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23322075 | 0.90 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23321719 | 0.90 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23321609 | 0.90 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23322166 | 0.90 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3669854-B1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITION | G C DENTAL IND CORP (JP) | 2026-04-08 | — | — | EP | disclosed |
| US-12465559-B2 | Fluorescent curable dental composition and cured product thereof | KURARAY NORITAKE DENTAL INC. (JP) | 2025-11-11 | — | — | US | disclosed |
| US-20250213434-A1 | DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY | KURARAY NORITAKE DENTAL INC. (JP) | 2025-07-03 | — | — | US | disclosed |
| US-20250206868-A1 | METHOD FOR PRODUCING TREATED-SILICA DISPERSED MONOMER COMPOSITION | GC CORPORATION (JP) | 2025-06-26 | — | — | US | disclosed |
| WO-2025126917-A1 | DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2025-06-19 | — | — | WO | disclosed |
| EP-4505992-A1 | DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY | Kuraray Noritake Dental Inc. (JP) | 2025-02-12 | — | — | EP | disclosed |
| EP-4501972-A1 | METHOD FOR PRODUCING TREATED-SILICA DISPERSED MONOMER COMPOSITION | GC Corporation (JP) | 2025-02-05 | — | — | EP | disclosed |
| EP-3373887-B1 | KIT OF PARTS FOR PRODUCING A GLASS IONOMER CEMENT, PROCESS OF PRODUCTION AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-11-27 | — | — | EP | disclosed |
| EP-3586814-B1 | DENTAL CURABLE COMPOSITION | G C DENTAL IND CORP (JP) | 2024-01-31 | — | — | EP | disclosed |
| US-20230381066-A1 | DENTAL CURABLE COMPOSITION HAVING GOOD COLOR COMPATIBILITY | KURARAY NORITAKE DENTAL INC. (JP) | 2023-11-30 | — | — | US | disclosed |
| CN-102083403-A | Dental composition and composite resin | KURARAY MEDICAL INC | 2011-06-01 | — | — | CN | disclosed |
| US-7951851-B2 | Curable composition for dental purposes | KURARAY MEDICAL INC. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20110046261-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | KURARAY MEDICAL INC. (JP) | 2011-02-24 | — | — | US | disclosed |
| EP-2275076-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | Kuraray Medical Inc. (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20100105802-A1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | KURARAY MEDICAL INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| CN-101600412-A | Curable composition for dental use | KURARAY MEDICAL INC (JP) | 2009-12-09 | — | — | CN | disclosed |
| EP-2123247-A1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | Kuraray Medical Inc. (JP) | 2009-11-25 | — | — | EP | disclosed |
| EP-0639576-B1 | Organopolysiloxanes having a silanol group and process of making them | SHINETSU CHEMICAL CO (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-5508369-A | ROOM TEMPERATURE CURABLE LIQUID SILICONE RUBBER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0639576-A1 | Organopolysiloxanes having a silanol group and process of making them | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105802-A1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | H1-0, H1-3, H1-2 | TSHR 2517/4885POLB 696/4885APEX1 1834/4885 |
| US-12465559-B2 | Fluorescent curable dental composition and cured product thereof | BRD1, TBCA, BAZ1A | TSHR 4128/4885POLB 402/4885APEX1 2291/4885 |
| US-20110046261-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | CAD, KATNAL2, ZYX | TSHR 3309/4885POLB 623/4885APEX1 4096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.