Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805448 | 0.95 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15477542 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9805470 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15477537 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1023058 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31679623 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8087340 | 0.90 | THRB (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL692374 | 0.89 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL6510428 | 0.89 | THRB (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL476606 | 0.87 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 867 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12358933-B2 | Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method | PIOCEL CO., LTD. (KR) | 2025-07-15 | — | — | US | claimed |
| US-20250109153-A1 | A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method | PIOCEL CO., LTD. (KR) | 2025-04-03 | — | — | US | claimed |
| CN-119264633-A | Flame-retardant fireproof plastic and preparation method thereof | 青岛东一岳新材料有限公司 | 2025-01-07 | — | — | CN | claimed |
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2024-12-12 | — | — | US | claimed |
| EP-4448536-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. (US) | 2024-10-23 | — | — | EP | claimed |
| CN-118401532-A | High-purity polysiloxane macromer and preparation method thereof | 盖列斯特有限公司 | 2024-07-26 | — | — | CN | claimed |
| US-11814534-B2 | Clay-polyacrylate composites suspension via in situ polymerization | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-11-14 | — | — | US | claimed |
| WO-2023153586-A1 | NOVEL META-POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (META-POSS) COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION COMPRISING META-POSS COMPOUND PRODUCED THEREBY | 주식회사 파이오셀 | 2023-08-17 | — | — | WO | claimed |
| US-20230212417-A1 | CLAY-POLYACRYLATE COMPOSITES SUSPENSION VIA IN SITU POLYMERIZATION | AGENCY SCIENCE TECH & RES (SG) | 2023-07-06 | — | — | US | claimed |
| WO-2023113779-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. (US) | 2023-06-22 | — | — | WO | claimed |
| WO-1999017716-A2 | DENTAL MATERIALS HAVING A NANOSCALE FILLER | DENTSPLY INTERNATIONAL INC. (US) | 1999-04-15 | — | — | WO | claimed |
| US-5811565-A | TREATING MIXTURE WITH LEWIS ACID HALIDE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| WO-1998037127-A1 | ORGANIC/INORGANIC COMPOSITES WITH LOW HYDROXYL GROUP CONTENT, METHOD FOR THEIR PRODUCTION AND APPLICATION | INSTITUT FÜR NEUE MATERIALIEN GEM. GMBH (DE) | 1998-08-27 | — | — | WO | claimed |
| EP-0799851-A2 | Preparation of polyorganosilloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-10-08 | — | — | EP | claimed |
| US-5629401-A | Preparation of polyorganosiloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-05-13 | — | — | US | claimed |
| EP-0593297-B1 | Resin composition for coating and paint | HITACHI CHEMICAL CO LTD (JP) | 1997-04-16 | — | — | EP | claimed |
| US-5539051-A | ACRYLATE RESIN AND ADDITION TYPE RESIN WITH PENDANT SILICON CONTAINING GROUPS, FOR CONCRETE, MASONRY, NONSTAINING | HITACHI CHEMICAL COMPANY CO., LTD. (JP) | 1996-07-23 | — | — | US | claimed |
| US-5039761-A | Addition-condensation copolymers; waterproofing, sliding, gas permeability | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-08-13 | — | — | US | claimed |
| US-5023159-A | Encapsulated electrophotographic toner compositions | XEROX CORPORATION (US) | 1991-06-11 | — | — | US | claimed |
| EP-0311348-A2 | Novel macromers containing a polyether moiety, process of preparing them and polymers thereof | Nippon Oil Co., Ltd. (JP) | 1989-04-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358933-B2 | Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method | SPEN, SAE1, OSTC | TSHR 3556/4885THRB 3131/4885POLB 925/4885 |
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | SSRP1, RPLP2, RPLP1 | TSHR 1897/4885THRB 2939/4885POLB 307/4885 |
| US-20250109153-A1 | A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method | SPEN, SAE1, SOST | TSHR 3789/4885THRB 3126/4885POLB 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.