Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL6437660 | 1.00 | TDP1 (0.50) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL10484401 | 1.00 | TDP1 (0.50) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL819744 | 1.00 | — | — | |
| Methacrylic Acid SCHEMBL11319477 | 0.96 | TDP1 (0.47) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL491341 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL15005463 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL2230382 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL13234423 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL11235035 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL15043 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10159630-B2 | Two- and three-component siloxane and related compounds and compositions | KIMMERLING HOLDINGS GROUP, LLC (US) | 2018-12-25 | — | — | US | disclosed |
| US-20160199266-A1 | TWO- AND THREE-COMPONENT SILOXANE AND RELATED COMPOUNDS AND COMPOSITIONS | KIMMERLING HOLDINGS GROUP, LLC | 2016-07-14 | — | — | US | disclosed |
| US-9314407-B2 | Two- and three-component siloxanes and related compounds and compositions | KIMMERLING HOLDINGS GROUP, LLC (US) | 2016-04-19 | — | — | US | disclosed |
| EP-2661648-A1 | POLYHETEROSILOXANES FOR HIGH REFRACTIVE INDEX MATERIALS | Dow Corning Corporation (US) | 2013-11-13 | — | — | EP | disclosed |
| EP-2661647-A1 | POLYHETEROSILOXANES FOR ANTIMICROBIAL MATERIALS | Dow Corning Corporation (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20130230676-A1 | Two- and Three-Component Siloxanes and Related Compounds and Compositions | KIMMERLING HOLDINGS GROUP, LLC | 2013-09-05 | — | — | US | disclosed |
| WO-2012094450-A1 | POLYHETEROSILOXANES FOR HIGH REFRACTIVE INDEX MATERIALS | DOW CORNING CORPORATION (US) | 2012-07-12 | — | — | WO | disclosed |
| WO-2012094457-A1 | POLYHETEROSILOXANES FOR ANTIMICROBIAL MATERIALS | DOW CORNING CORPORATION (US) | 2012-07-12 | — | — | WO | disclosed |
| EP-2448999-A1 | METHODS FOR PREPARING POLYHETEROSILOXANES | Dow Corning Corporation (US) | 2012-05-09 | — | — | EP | disclosed |
| EP-1809706-B1 | SUBSTRATE WITH AN ANTI-SOILING COATING | ESSILOR INT (FR) | 2012-05-02 | — | — | EP | disclosed |
| WO-2011002826-A1 | METHODS FOR PREPARING POLYHETEROSILOXANES | DOW CORNING CORPORATION (US) | 2011-01-06 | — | — | WO | disclosed |
| US-7678464-B2 | Substrate with anti-soiling coating | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-03-16 | — | — | US | disclosed |
| EP-1809706-A1 | SUBSTRATE WITH AN ANTI-SOILING COATING | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 2007-07-25 | — | — | EP | disclosed |
| US-20070026237-A1 | Substrate with anti-soiling coating | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2007-02-01 | — | — | US | disclosed |
| WO-2006045582-A1 | SUBSTRATE WITH AN ANTI-SOILING COATING | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10159630-B2 | Two- and three-component siloxane and related compounds and compositions | ITGB3, ITGA2, ITGB2 | TDP1 4755/4885FFAR3 2776/4885LCK 3320/4885 |
| US-20130230676-A1 | Two- and Three-Component Siloxanes and Related Compounds and Compositions | ITGA2, ITGB3, ITGA4 | TDP1 4762/4885FFAR3 2449/4885LCK 3794/4885 |
| US-20160199266-A1 | TWO- AND THREE-COMPONENT SILOXANE AND RELATED COMPOUNDS AND COMPOSITIONS | ITGB3, ITGA2, ITGB2 | TDP1 4755/4885FFAR3 2776/4885LCK 3320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.