Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | PPARA | Q07869 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475815 | 0.91 | MEN1 (0.44) | PPARGPPARAMEN1KMT2AHPGD | |
| SCHEMBL36007 | 0.86 | PPARG (0.43) | PPARGPPARAMEN1KMT2AHPGD | |
| SCHEMBL3817347 | 0.82 | MEN1 (0.59) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL6472219 | 0.80 | MEN1 (0.41) | PPARAMEN1KMT2AHPGDNPC1 | |
| SCHEMBL9123311 | 0.77 | CYP4F2 (0.38) | KMT2AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL5153519 | 0.77 | PPARD (0.42) | PPARGPPARADRD2DRD1DRD4 | |
| SCHEMBL2392159 | 0.77 | KDM4E (0.47) | MEN1KMT2AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL4838343 | 0.76 | CYP4A11 (0.47) | HPGDNPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4376769 | 0.75 | DRD2 (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL4774778 | 0.74 | CYP4A11 (0.47) | HPGDNPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814847-B1 | NOVEL METHOD FOR PREPARING 3-[5'-(3,4-BIS-HYDROXYMETHYL-BENZYLOXY)-2'- ETHYL-2-PROPYL-BIPHENYL-4-YL]-PENTA-3-OL | GALDERMA RES & DEV (FR) | 2011-01-12 | — | — | EP | claimed |
| US-7638657-B2 | Preparation of 3-[5′-(3,4-bis(hydroxymethyl)benzyloxy)-2′-ethyl-2-propylbiphenyl-4-yl]pentan-3-ol | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-12-29 | — | — | US | claimed |
| US-20070282136-A1 | Preparation of 3-[5'-(3,4-bis(hydroxymethyl)benzyloxy)-2'-ethyl-2-propylbiphenyl-4-yl]pentan-3-ol | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-12-06 | — | — | US | claimed |
| US-7638657-B2 | Preparation of 3-[5′-(3,4-bis(hydroxymethyl)benzyloxy)-2′-ethyl-2-propylbiphenyl-4-yl]pentan-3-ol | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-12-29 | — | — | US | disclosed |
| US-20070282136-A1 | Preparation of 3-[5'-(3,4-bis(hydroxymethyl)benzyloxy)-2'-ethyl-2-propylbiphenyl-4-yl]pentan-3-ol | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-12-06 | — | — | US | disclosed |
| US-6924400-B2 | Triaromatic vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2005-08-02 | — | — | US | disclosed |
| US-20030195259-A1 | Triaromatic vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195259-A1 | Triaromatic vitamin D analogues | CYP24A1, CYP2R1, VDR | PPARG 96/4885PPARA 204/4885MEN1 945/4885 |
| US-20070282136-A1 | Preparation of 3-[5'-(3,4-bis(hydroxymethyl)benzyloxy)-2'-ethyl-2-propylbiphenyl-4-yl]pentan-3-ol | PARP2, CYP4B1, CYP8B1 | PPARG 1515/4885PPARA 1082/4885MEN1 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.