Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023633 | 0.91 | PPARG (0.46) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL3817347 | 0.85 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL6472219 | 0.83 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL13678676 | 0.78 | KDM4E (0.43) | KMT2ASMN1; SMN2KDM4EDRD2DRD1 | |
| SCHEMBL6511762 | 0.77 | DRD2 (0.39) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28334586 | 0.77 | SLC6A2 (0.40) | MAPTL3MBTL1DRD2DRD1DRD4 | |
| SCHEMBL36007 | 0.76 | PPARG (0.43) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL14421954 | 0.76 | NPC1 (0.47) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL9123311 | 0.75 | CYP4F2 (0.38) | KMT2ASMN1; SMN2HPGDNPC1L3MBTL1 | |
| SCHEMBL22032224 | 0.74 | ALDH1A1 (0.40) | MEN1KMT2AHPGDALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100376530-C | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2008-03-26 | — | — | CN | disclosed |
| US-6924400-B2 | Triaromatic vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2005-08-02 | — | — | US | disclosed |
| CN-1620414-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2005-05-25 | — | — | CN | disclosed |
| US-20030195259-A1 | Triaromatic vitamin D analogues | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195259-A1 | Triaromatic vitamin D analogues | CYP24A1, CYP2R1, VDR | MEN1 945/4885KMT2A 4353/4885SMN1; SMN2 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.