Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.67 |
| ▸ | TK1 | P04183 | 7/20 | 0.53 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10239450 | 0.86 | DHFR (0.64) | DHFRTK1NT5M | |
| SCHEMBL15865916 | 0.85 | DHFR (0.59) | DHFRTK1NT5M | |
| SCHEMBL29144164 | 0.82 | DHFR (0.73) | DHFRTK1NT5M | |
| SCHEMBL17826619 | 0.81 | DHFR (0.49) | DHFRTK1 | |
| SCHEMBL1619438 | 0.81 | DHFR (1.00) | DHFRTK1NT5M | |
| SCHEMBL30968383 | 0.81 | DHFR (1.00) | DHFRTK1NT5M | |
| SCHEMBL16558263 | 0.81 | DHFR (1.00) | DHFRTK1NT5M | |
| SCHEMBL12303789 | 0.80 | DHFR (0.67) | DHFRTK1NT5M | |
| SCHEMBL2455603 | 0.80 | DHFR (0.67) | DHFRTK1NT5M | |
| SCHEMBL31084252 | 0.80 | DHFR (0.67) | DHFRTK1NT5M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170002037-A1 | CYCLIC NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. | 2017-01-05 | — | — | US | disclosed |
| US-8772474-B2 | Cyclic nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| WO-2012088155-A1 | CYCLIC NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002037-A1 | CYCLIC NUCLEOTIDE ANALOGS | NT5C2, NTPCR, PNP | DHFR 363/4885TK1 46/4885NT5M 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.