SCHEMBL16558263

SCHEMBL16558263

Cc1cn([C@H]2CC3OP(=O)(O)OCC3O2)c(=O)[nH]c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 1.00
TK1 P04183 5/20 0.53
NT5M Q9NPB1 1/20 0.48
STING1 Q86WV6 1/20 0.47
ALB P02768 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1619438 1.00 DHFR (1.00) DHFRTK1NT5MSTING1ALB
SCHEMBL30968383 1.00 DHFR (1.00) DHFRTK1NT5MSTING1ALB
SCHEMBL2408425 0.86 DHFR (0.75) DHFRSTING1
SCHEMBL29144164 0.85 DHFR (0.73) DHFRTK1NT5MALBPKM
SCHEMBL10239772 0.84 DHFR (0.72) DHFRTK1NT5M
SCHEMBL24852241 0.81 DHFR (0.68) DHFRTK1NT5MALBPKM
SCHEMBL23105032 0.81 DHFR (0.68) DHFRTK1NT5MALBPKM
SCHEMBL12303789 0.81 DHFR (0.67) DHFRTK1NT5MALBPKM
SCHEMBL31084252 0.81 DHFR (0.67) DHFRTK1NT5MALBPKM
SCHEMBL2455603 0.81 DHFR (0.67) DHFRTK1NT5MALBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11819550-B2 Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) EAGLE BIOLOGICS, INC. (US) 2023-11-21 US disclosed
US-11819550-B2 Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) EAGLE BIOLOGICS, INC. (US) 2023-11-21 US disclosed
US-10821184-B2 Liquid protein formulations containing thiamine pyrophosphate (TPP) EAGLE BIOLOGICS, INC. (US) 2020-11-03 US disclosed
US-20180153997-A1 Liquid Protein Formulations Containing Organophosphates EAGLE BIOLOGICS, INC. 2018-06-07 US disclosed
US-20180153997-A1 Liquid Protein Formulations Containing Organophosphates EAGLE BIOLOGICS, INC. 2018-06-07 US disclosed
US-9913905-B2 Liquid pharmaceutical formulations for injection comprising thiamine pyrophosphate 1-(3-aminopropyl)-2-methyl-1H-imidazole and uses thereof EAGLE BIOLOGICS, INC. (US) 2018-03-13 US disclosed
US-9913905-B2 Liquid pharmaceutical formulations for injection comprising thiamine pyrophosphate 1-(3-aminopropyl)-2-methyl-1H-imidazole and uses thereof EAGLE BIOLOGICS, INC. (US) 2018-03-13 US disclosed
WO-2016054259-A1 POLYSACCHARIDE AND NUCLEIC ACID FORMULATIONS CONTAINING VISCOSITY-LOWERING AGENTS Arsia Therapeutics, Inc. (US) 2016-04-07 WO disclosed
US-20150071921-A1 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES EAGLE BIOLOGICS, INC. 2015-03-12 US disclosed
US-20150071921-A1 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES EAGLE BIOLOGICS, INC. 2015-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11819550-B2 Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) PDE7A, PDE8A, PDE8B DHFR 4463/4885TK1 561/4885NT5M 1113/4885
US-10821184-B2 Liquid protein formulations containing thiamine pyrophosphate (TPP) PLPBP, ITPA, PLTP DHFR 548/4885TK1 114/4885NT5M 1261/4885
US-20150071921-A1 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES IGFBP1, IGFBP5, IGF2BP1 DHFR 3700/4885TK1 2774/4885NT5M 3247/4885
US-20180153997-A1 Liquid Protein Formulations Containing Organophosphates IGFBP1, IGFBP5, IGF2BP1 DHFR 3700/4885TK1 2774/4885NT5M 3247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.