SCHEMBL29144164

SCHEMBL29144164

Cc1cn(C2CC3OP(=O)([O-])OCC3O2)c(=O)[nH]c1=O.[Na+]

nearest known ligand 0.73

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DHFR known ✓ P00374 1/20 0.73
TK1 P04183 5/20 0.49
NT5M Q9NPB1 1/20 0.45
ALB P02768 1/20 0.43
PKM P14618 1/20 0.43
LMNA P02545 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16558263 0.85 DHFR (1.00) DHFRTK1NT5MALBPKM
SCHEMBL30968383 0.85 DHFR (1.00) DHFRTK1NT5MALBPKM
SCHEMBL1619438 0.85 DHFR (1.00) DHFRTK1NT5MALBPKM
SCHEMBL10239772 0.83 DHFR (0.72) DHFRTK1NT5M
SCHEMBL10239456 0.82 DHFR (0.67) DHFRTK1NT5M
SCHEMBL24852241 0.80 DHFR (0.68) DHFRTK1NT5MALBPKM
SCHEMBL23105032 0.80 DHFR (0.68) DHFRTK1NT5MALBPKM
SCHEMBL31084252 0.80 DHFR (0.67) DHFRTK1NT5MALBPKM
SCHEMBL12303789 0.80 DHFR (0.67) DHFRTK1NT5MALBPKM
SCHEMBL2455603 0.80 DHFR (0.67) DHFRTK1NT5MALBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117012973-B Positive pole piece of sodium ion battery and sodium ion battery 江苏天鹏电源有限公司 2023-12-26 CN disclosed
CN-117239240-A Nonaqueous electrolyte and high-voltage lithium ion battery 合肥市赛纬电子材料有限公司 2023-12-15 CN disclosed
CN-117012973-A Positive pole piece of sodium ion battery and sodium ion battery 江苏天鹏电源有限公司 2023-11-07 CN disclosed