Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | TK1 | P04183 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 5/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17826617 | 0.86 | DHFR (0.44) | DHFRTK1ALDH1A1LMNAALB | |
| SCHEMBL8827975 | 0.82 | TK1 (0.52) | DHFRTK1ALDH1A1LMNAALB | |
| SCHEMBL8745678 | 0.82 | TK1 (0.52) | DHFRTK1ALDH1A1LMNAALB | |
| SCHEMBL10239456 | 0.81 | DHFR (0.67) | DHFRTK1 | |
| SCHEMBL17826624 | 0.80 | DHFR (0.53) | DHFRTK1ALDH1A1LMNAALB | |
| SCHEMBL17826611 | 0.79 | DHFR (0.45) | DHFRTK1 | |
| SCHEMBL5982146 | 0.74 | ALDH1A1 (0.49) | DHFRTK1ALDH1A1LMNAALB | |
| SCHEMBL9218555 | 0.74 | ALDH1A1 (0.49) | DHFRTK1ALDH1A1LMNAALB | |
| SCHEMBL20056925 | 0.73 | SLC28A1 (0.43) | STING1 | |
| SCHEMBL16158819 | 0.73 | STING1 (0.33) | ALDH1A1BLMSTING1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365605-B2 | Cyclic nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2016-06-14 | — | — | US | disclosed |