SCHEMBL1023977

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3589994	0.78	NOTUM (0.47)	NOTUMCA1CA2MAPK1CYP3A4
	SCHEMBL5042495	0.78	POLB (0.37)	NOTUMMAPK1ALDH1A1
	SCHEMBL5508293	0.77	GLA (0.34)	ALDH1A1HPGDHSD17B10
	SCHEMBL3540180	0.75	NOTUM (0.44)	NOTUMCA1CA2CYP3A4CA12
	SCHEMBL23226961	0.75	NOTUM (0.44)	NOTUMMAPK1CYP3A4HTR3ACYP1A2
	SCHEMBL17744456	0.75	NOTUM (0.44)	NOTUMMAPK1CYP3A4ALDH1A1HSD17B10
	SCHEMBL12955319	0.75	TSHR (0.39)	CYP3A4ALDH1A1ALOX15HSD17B10
	SCHEMBL24945813	0.73	NOTUM (0.42)	NOTUMMAPK1CYP3A4ALDH1A1HPGD
	SCHEMBL28844353	0.73	ALDH1A1 (0.46)	NOTUMALDH1A1HPGDSMN1; SMN2HSD17B10
	SCHEMBL12804773	0.72	NOTUM (0.41)	NOTUMCA1CA2MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.