SCHEMBL1024003

SCHEMBL1024003

C=Cc1ccc(Sc2ccc(C=C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
TSHR P16473 2/20 0.48
NR1H2 P55055 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
HDAC8 Q9BY41 2/20 0.40
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
DDAH1 O94760 1/20 0.35
NOS1 P29475 1/20 0.35
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium SCHEMBL30427541 0.97 ALDH1A1 (0.61) ALDH1A1TSHRNR1H2CYP3A4MAPK1
SCHEMBL942072 0.90 ALDH1A1 (0.59) ALDH1A1TSHRNR1H2CYP3A4MAPK1
SCHEMBL16709768 0.90 ALDH1A1 (0.59) ALDH1A1TSHRNR1H2CYP3A4MAPK1
SCHEMBL14289218 0.88 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4TDP1HDAC8
SCHEMBL16709773 0.88 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8LMNA
SCHEMBL9888795 0.86 ALDH1A1 (0.48) ALDH1A1TSHRNR1H2CYP3A4MAPK1
SCHEMBL16709769 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTDP1HDAC8CHRNA7
SCHEMBL4252557 0.82 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL2705727 0.81 ALDH1A1 (0.42) ALDH1A1TSHRHDAC8LMNAHPGD
SCHEMBL16709761 0.81 SMN1; SMN2 (0.44) ALDH1A1TSHRCYP3A4MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117089285-A Automobile tail lamp repairing method 李永均 2023-11-21 CN claimed
CN-104521019-B Organic semiconductor preparaton 默克专利股份有限公司 2018-12-07 CN claimed
US-9151968-B2 Integrated optical waveguide interferometric sensor OPTISENSE B.V. (NL) 2015-10-06 US claimed
CN-104521019-A Organic semiconducting formulation MERCK PATENT GMBH 2015-04-15 CN claimed
EP-1928395-B1 DENTAL MATERIAL GDF GES FÜR DENTALE FORSCHUNG UND INNOVAT (DE) 2015-03-11 EP claimed
CN-101606106-B Volume phase hologram recording material and optical information recording medium NIPPON STEEL CHEMICAL CO 2012-10-17 CN claimed
WO-2010089209-A1 INTEGRATED OPTICAL WAVEGUIDE INTERFEROMETRIC SENSOR OPTISENSE B.V. (NL) 2010-08-12 WO claimed
EP-2214049-A1 Integrated optical waveguide interferometric sensor Optisense B.V. (NL) 2010-08-04 EP claimed
CN-101606106-A Volume phase hologram recording material and optical information recording medium NIPPON STEEL CHEMICAL CO (JP) 2009-12-16 CN claimed
US-20090298966-A1 DENTAL MATERIAL GDF GESELLSCHAFT FUR DENTALE FORSCHUNG UND INNOVATIONEN GMBH (DE) 2009-12-03 US claimed
EP-1165505-A1 CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS ABBOTT LABORATORIES (US) 2002-01-02 EP claimed
EP-1140814-A2 CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS ABBOTT LABORATORIES (US) 2001-10-10 EP claimed
WO-2000059880-A1 CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS ABBOTT LABORATORIES (US) 2000-10-12 WO claimed
WO-2000039081-A2 CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS ABBOTT LABORATORIES (US) 2000-07-06 WO claimed
US-4234674-A Amino-functional photopolymer compositions and photo-oxidation imaging processes employing same MONSANTO COMPANY (US) 1980-11-18 US claimed
US-4188223-A Amino-functional photopolymer compositions and photo-oxidation imaging processes employing same MONSANTO COMPANY (US) 1980-02-12 US claimed
CN-118287153-A Palladium-based catalyst supported by phosphine sulfide polymer and preparation and application thereof 中国科学院大连化学物理研究所 2024-07-05 CN disclosed
CN-117296162-A Uranium-based phosphors and compositions for display and lighting applications 通用电气公司 2023-12-26 CN disclosed
US-4234674-A Amino-functional photopolymer compositions and photo-oxidation imaging processes employing same MONSANTO COMPANY (US) 1980-11-18 US disclosed
US-4188223-A Amino-functional photopolymer compositions and photo-oxidation imaging processes employing same MONSANTO COMPANY (US) 1980-02-12 US disclosed