SCHEMBL16709769

SCHEMBL16709769

C=Cc1ccc(Sc2cccc(Sc3ccccc3)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 1/20 0.50
MAOA P21397 3/20 0.43
MAOB P27338 3/20 0.43
HTR2C P28335 2/20 0.42
HTR6 P50406 1/20 0.42
KDR P35968 1/20 0.39
BCL2 P10415 1/20 0.39
MCL1 Q07820 1/20 0.39
SLC6A4 P31645 1/20 0.38
HPGD P15428 1/20 0.37
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ANXA2 P07355 1/20 0.36
S100A10 P60903 1/20 0.36
PLA2G1B P04054 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
SIRT1 Q96EB6 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16709768 0.92 ALDH1A1 (0.59) ALDH1A1TSHRMAOAMAOBHTR2C
SCHEMBL942072 0.92 ALDH1A1 (0.59) ALDH1A1TSHRMAOAMAOBHTR2C
SCHEMBL28687409 0.86 ALDH1A1 (0.52) ALDH1A1TSHRMAOAMAOBHTR2C
Diphenylsulfane SCHEMBL28268221 0.85 ALDH1A1 (0.70) ALDH1A1TSHRMAOAMAOBHTR2C
SCHEMBL3902722 0.82 MAOA (0.56) ALDH1A1TSHRMAOAMAOBHTR2C
SCHEMBL3903397 0.82 MAOA (0.56) ALDH1A1TSHRMAOAMAOBHTR2C
SCHEMBL3903581 0.82 MAOA (0.56) ALDH1A1TSHRMAOAMAOBHTR2C
SCHEMBL1024003 0.82 ALDH1A1 (0.65) ALDH1A1TSHRMAOAMAOBHPGD
SCHEMBL3889262 0.82 MAOA (0.56) ALDH1A1TSHRMAOAMAOBHTR2C
SCHEMBL3904216 0.82 MAOA (0.56) ALDH1A1TSHRMAOAMAOBHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015068839-A1 POLYMERIZABLE COMPOUND, RESIN COMPOSITION USING SAME, CURED RESIN, AND OPTICAL MATERIAL 新日鉄住金化学株式会社 2015-05-14 WO disclosed