SCHEMBL16709773

SCHEMBL16709773

C=Cc1ccc(Sc2ccc(SC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
CYP1A1 P04798 8/20 0.44
CYP1A2 P05177 8/20 0.44
CYP1B1 Q16678 8/20 0.44
FBP1 P09467 1/20 0.41
XDH P47989 1/20 0.40
TSHR P16473 1/20 0.39
HDAC8 Q9BY41 1/20 0.38
GSK3B P49841 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98657 0.93 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1
SCHEMBL1024003 0.88 ALDH1A1 (0.65) ALDH1A1TSHRHDAC8LMNA
Lithium SCHEMBL30427541 0.85 ALDH1A1 (0.61) ALDH1A1TSHRHDAC8LMNA
SCHEMBL14289218 0.82 ALDH1A1 (0.50) ALDH1A1TSHRHDAC8KDM4ELMNA
SCHEMBL7033576 0.80 ALDH1A1 (0.50) ALDH1A1CYP1A1CYP1A2CYP1B1TSHR
SCHEMBL16709768 0.79 ALDH1A1 (0.59) ALDH1A1TSHRHDAC8MAPT
SCHEMBL942072 0.79 ALDH1A1 (0.59) ALDH1A1TSHRHDAC8MAPT
SCHEMBL19914058 0.77 ALDH1A1 (0.86) ALDH1A1CYP1A1CYP1A2CYP1B1FBP1
SCHEMBL9888795 0.76 ALDH1A1 (0.48) ALDH1A1TSHRHDAC8LMNA
SCHEMBL16709778 0.74 SLC6A4 (0.37) ALDH1A1CYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015068839-A1 POLYMERIZABLE COMPOUND, RESIN COMPOSITION USING SAME, CURED RESIN, AND OPTICAL MATERIAL 新日鉄住金化学株式会社 2015-05-14 WO disclosed