SCHEMBL4252557

SCHEMBL4252557

C=Cc1ccc(SSc2ccc(C=C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 2/20 0.41
HDAC8 Q9BY41 2/20 0.40
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MGLL Q99685 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TP53 P04637 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27762045 0.89 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL1024003 0.82 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8HPGD
SCHEMBL473081 0.80 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8MAPT
SCHEMBL7639 0.80 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8MAPT
Lithium SCHEMBL30427541 0.80 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HDAC8HPGD
SCHEMBL16652461 0.79 ALDH1A1 (0.46) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL98657 0.78 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8MAPTSMN1; SMN2
SCHEMBL18726334 0.78 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL20609645 0.78 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL18649595 0.78 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115954539-A Self-healing mesh polymer electrolyte, preparation method and application thereof, and polymer lithium battery 吉林省翰驰科技有限公司 2023-04-11 CN claimed
WO-2017187279-A1 HEALABLE THERMOPLASTIC RESINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-11-02 WO claimed
CN-115954539-B Self-healing reticular polymer electrolyte, preparation method and application thereof, and polymer lithium battery 吉林省东驰新能源科技有限公司 2025-01-28 CN disclosed
WO-2023079966-A1 CROSSLINKABLE RESIN COMPOSITION AND CURED ARTICLE DIC株式会社 2023-05-11 WO disclosed
CN-115954539-A Self-healing mesh polymer electrolyte, preparation method and application thereof, and polymer lithium battery 吉林省翰驰科技有限公司 2023-04-11 CN disclosed
US-10821082-B2 Disintegratable core/shell silica particles for encapsulating and releasing bioactive macromolecules UNIVERSITE DE STRASBOURG (FR) 2020-11-03 US disclosed
US-10450423-B2 Disintegratable porous organometaloxyde material UNIVERSITE DE STRASBOURG (FR) 2019-10-22 US disclosed
WO-2017187279-A1 HEALABLE THERMOPLASTIC RESINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-11-02 WO disclosed
WO-2017187279-A1 HEALABLE THERMOPLASTIC RESINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-11-02 WO disclosed
US-20170119688-A1 Disintegratable Core/Shell Silica Particles for Encapsulating and Releasing Bioactive Macromolecules UNIVERSITE DE STRASBOURG (FR) 2017-05-04 US disclosed
JP-2009249357-A 1-VINYL-4-[(4-VINYLPHENYL)DISULFANYL]BENZENE DERIVATIVE TOYO KASEI KOGYO CO LTD 2009-10-29 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10450423-B2 Disintegratable porous organometaloxyde material MCM4, SI, ESD ALDH1A1 3969/4885TSHR 4866/4885TDP1 1811/4885
US-10821082-B2 Disintegratable core/shell silica particles for encapsulating and releasing bioactive macromolecules VIP, ADAM9, ADAM17 ALDH1A1 4638/4885TSHR 3613/4885TDP1 2961/4885
US-20170119688-A1 Disintegratable Core/Shell Silica Particles for Encapsulating and Releasing Bioactive Macromolecules VIP, ADAM9, ADAM17 ALDH1A1 4638/4885TSHR 3613/4885TDP1 2961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.