Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023983 | 0.88 | SYK (0.42) | CTSSCTSLCTSBSIGMAR1MEN1 | |
| SCHEMBL4856705 | 0.84 | SYK (0.48) | IDO1SYKMMP1MMP3MMP9 | |
| SCHEMBL1024013 | 0.81 | SIGMAR1 (0.49) | CTSSCTSLCTSBIDO1AKT1 | |
| SCHEMBL1021128 | 0.80 | SIRT5 (0.45) | CTSSCTSLCTSBIDO1AKT1 | |
| SCHEMBL22833183 | 0.79 | CTSL (0.54) | CTSSCTSLCTSBIDO1AKT1 | |
| SCHEMBL1024008 | 0.79 | KMT2A (0.48) | CTSSCTSLCTSBIDO1AKT1 | |
| SCHEMBL1022335 | 0.74 | SYK (0.53) | MEN1KMT2ASYKMMP1MMP3 | |
| SCHEMBL5059307 | 0.74 | CTSL (0.47) | CTSSCTSLCTSBIDO1AKT1 | |
| SCHEMBL1024723 | 0.74 | CPB1 (0.47) | — | |
| SCHEMBL4848854 | 0.74 | SYK (0.46) | CTSSCTSLCTSBIDO1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797110-B1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AICURIS GMBH & CO KG (DE) | 2011-01-12 | — | — | EP | disclosed |