Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.43 |
| ▸ | OXTR | P30559 | 9/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316696 | 0.90 | HTR3A (0.43) | ADRB1HTR1AHTR1DHTR7HTR2B | |
| SCHEMBL82301 | 0.72 | ADRB1 (0.85) | ADRB1HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL315784 | 0.70 | OXTR (0.44) | OXTRAVPR1AAVPR2AVPR1B | |
| SCHEMBL9279127 | 0.70 | HTR3A (0.49) | ADRB1HTR1AHTR7HTR3AHTR6 | |
| SCHEMBL316872 | 0.68 | OXTR (0.39) | HTR2AHTR2BOXTRAVPR1AAVPR2 | |
| SCHEMBL21548392 | 0.66 | ADRB1 (0.79) | ADRB1HTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL8285404 | 0.65 | ADRB1 (0.56) | ADRB1HTR1AHTR2AHTR7HTR2B | |
| SCHEMBL4619815 | 0.65 | OXTR (0.49) | OXTRAVPR1AAVPR2AVPR1B | |
| SCHEMBL81940 | 0.65 | ADRB1 (1.00) | ADRB1HTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL6645952 | 0.65 | ADRB1 (1.00) | ADRB1HTR1AHTR1DHTR1BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093400-B2 | Compounds useful in therapy | PFIZER INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100317652-A1 | Compounds Useful In Therapy | PFIZER INC | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317652-A1 | Compounds Useful In Therapy | AVPR1A, AVPR1B, AVPR2 | ADRB1 280/4885HTR1A 49/4885HTR1D 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.