Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | MGMT | P16455 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL17275115 | 0.85 | MGMT (0.38) | ADORA1CDK1CCNB1MGMTCCNA2 | |
| SCHEMBL717431 | 0.83 | CA5A (0.39) | ADORA1CDK1CCNB1MGMTCCNA2 | |
| Phosphoric Acid SCHEMBL214567 | 0.81 | MGMT (0.44) | CDK1CCNB1MGMTCCNA2CDK2 | |
| SCHEMBL15167310 | 0.81 | TRPM2 (0.41) | — | |
| Adenine SCHEMBL2168804 | 0.80 | PI4KA (0.47) | ADORA1 | |
| SCHEMBL15166956 | 0.79 | TRPM2 (0.43) | — | |
| SCHEMBL136630 | 0.78 | CDK2 (0.49) | CDK1CCNB1MGMTCCNA2CDK2 | |
| SCHEMBL29677204 | 0.78 | CDK2 (0.49) | CDK1CCNB1MGMTCCNA2CDK2 | |
| Mercaptopurine Anhydrous SCHEMBL10522158 | 0.73 | ADORA1 (0.37) | ADORA1 | |
| SCHEMBL8102858 | 0.72 | ADORA1 (0.43) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274429-B1 | MULTIZYMES | DU PONT (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2274429-A1 | MULTIZYMES | E. I. du Pont de Nemours and Company (US) | 2011-01-19 | — | — | EP | disclosed |
| US-20110008868-A1 | MULTIZYMES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-01-13 | — | — | US | disclosed |
| WO-2009124225-A1 | MULTIZYMES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-10-08 | — | — | WO | disclosed |