Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 16/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172793 | 0.83 | P2RX7 (0.49) | P2RX7ALDH1A1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1372267 | 0.82 | P2RX7 (0.48) | P2RX7ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL14759859 | 0.82 | P2RX7 (0.48) | P2RX7ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL18255993 | 0.79 | P2RX7 (0.49) | P2RX7ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL2824162 | 0.77 | ALDH1A1 (0.54) | P2RX7ALDH1A1MEN1KMT2A | |
| SCHEMBL19403738 | 0.76 | ATM (0.55) | ALDH1A1 | |
| SCHEMBL14591562 | 0.75 | P2RX7 (0.52) | P2RX7MEN1KMT2A | |
| SCHEMBL15339827 | 0.74 | P2RX7 (0.45) | P2RX7ALDH1A1MEN1KMT2A | |
| SCHEMBL1928504 | 0.74 | GAA (0.67) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL13235907 | 0.73 | ALDH1A1 (0.42) | P2RX7ALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321731-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20160031820-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. | 2016-02-04 | — | — | US | disclosed |
| US-9096518-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140329836-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-11-06 | — | — | US | disclosed |
| US-8148373-B2 | Compounds | ASTRAZENECA AB (SE) | 2012-04-03 | — | — | US | disclosed |
| US-20090298807-A1 | Compounds | ASTRAZENECA AB (SE) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329836-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC5, HDAC1 | P2RX7 3181/4885ALDH1A1 1220/4885GAA 46/4885 |
| US-20090298807-A1 | Compounds | PKD1, SLC10A1, ABCB11 | P2RX7 1090/4885ALDH1A1 102/4885GAA 586/4885 |
| US-20160031820-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC5, HDAC1 | P2RX7 3469/4885ALDH1A1 1505/4885GAA 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.