Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242939 | 0.85 | SMN1; SMN2 (0.65) | ALDH1A1L3MBTL1HPGDMAPTKDM4E | |
| SCHEMBL10243085 | 0.82 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1HPGDMAPTKDM4E | |
| SCHEMBL10243027 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1L3MBTL1HPGDMAPTKDM4E | |
| SCHEMBL10242946 | 0.81 | SMN1; SMN2 (0.58) | ALDH1A1L3MBTL1HPGDMAPTKDM4E | |
| SCHEMBL28326194 | 0.80 | L3MBTL1 (0.73) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL6360275 | 0.79 | DRD2 (0.78) | L3MBTL1POLBSMN1; SMN2NAAADRD2 | |
| SCHEMBL15090257 | 0.78 | TAAR1 (0.49) | ALDH1A1HPGDMAPTPOLBKMT2A | |
| SCHEMBL10242978 | 0.77 | KEAP1 (0.58) | ALDH1A1L3MBTL1HPGDMAPTKDM4E | |
| SCHEMBL10282625 | 0.77 | KMT2A (0.54) | ALDH1A1L3MBTL1HPGDMAPTKDM4E | |
| SCHEMBL3092684 | 0.76 | ALDH1A1 (0.81) | ALDH1A1L3MBTL1HPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | ALDH1A1 1939/4885L3MBTL1 2853/4885HPGD 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.