Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351562 | 1.00 | MMP3 (0.52) | MMP3ALDH1A1HDAC2KIF11CA12 | |
| SCHEMBL127502 | 0.93 | ALDH1A1 (0.58) | MMP3ALDH1A1HDAC2CA12CA2 | |
| Benzene SCHEMBL28598325 | 0.88 | ALDH1A1 (0.52) | ALDH1A1CA12CA2CA9KDM4E | |
| SCHEMBL12567409 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HDAC2CA12CA2CA9 | |
| Styrene SCHEMBL11503937 | 0.84 | ALDH1A1 (0.61) | ALDH1A1CA12CA2CA9KDM4E | |
| Bicarbonate SCHEMBL3087568 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HDAC2CA12CA2CA9 | |
| SCHEMBL2304245 | 0.83 | ALDH1A1 (0.46) | MMP3ALDH1A1HDAC2CA12CA2 | |
| SCHEMBL28100998 | 0.83 | ALDH1A1 (0.46) | MMP3ALDH1A1HDAC2CA12CA2 | |
| Water SCHEMBL7178879 | 0.83 | ALDH1A1 (0.73) | ALDH1A1HDAC2CA1MEN1KMT2A | |
| Styrene SCHEMBL27589633 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CA12CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018868-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEINS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-02-09 | — | — | WO | disclosed |