Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808169 | 0.78 | — | — | |
| SCHEMBL12837233 | 0.77 | HDAC1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL12332937 | 0.77 | HDAC4 (0.33) | ALDH1A1LMNA | |
| SCHEMBL14017948 | 0.74 | — | — | |
| SCHEMBL27433930 | 0.73 | PAOX (0.34) | ALDH1A1ACHEPAOX | |
| SCHEMBL11194433 | 0.73 | CES2 (0.46) | ALDH1A1 | |
| SCHEMBL13675087 | 0.73 | — | — | |
| SCHEMBL6437517 | 0.72 | — | — | |
| SCHEMBL1987903 | 0.70 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2ACHEPAOX | |
| SCHEMBL10001 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040897-A1 | NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2012-02-16 | — | — | US | disclosed |
| US-7442809-B2 | Method for producing 1,3-dioxolan-4,6-dione compound | FUJIFILM CORPORATION (JP) | 2008-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040897-A1 | NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES | NR1D2, STARD10, NR1D1 | ALDH1A1 3340/4885LMNA 2921/4885SLC15A2 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.