SCHEMBL10243630

SCHEMBL10243630

CCN(CCNC(=O)OC)C(C)c1ccn(C)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31
REN P00797 6/20 0.31
CYP2D6 P10635 2/20 0.31
CYP1A2 P05177 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.31
MTNR1A P48039 2/20 0.31
MTNR1B P49286 2/20 0.31
CYP3A4 P08684 1/20 0.30
MEN1 O00255 1/20 0.30
HSP90AA1 P07900 1/20 0.30
KMT2A Q03164 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10243497 0.81 SLC22A1 (0.43) CYP2D6CYP1A2SMN1; SMN2MTNR1AMTNR1B
SCHEMBL10243510 0.80 ALOX5 (0.40) EPHX1SMN1; SMN2
SCHEMBL10243491 0.79 MEN1 (0.45) CYP1A2SMN1; SMN2MEN1HSP90AA1KMT2A
SCHEMBL10243623 0.79 HPGD (0.40) CYP2D6MAPTMTNR1AMTNR1BCYP3A4
SCHEMBL10244079 0.79 ALDH1A1 (0.40) SMN1; SMN2MAPTKMT2ATSHR
SCHEMBL10243433 0.79 MAPT (0.43) CYP2D6SMN1; SMN2MAPTMTNR1AMTNR1B
SCHEMBL10244695 0.79 SMN1; SMN2 (0.41) CYP2D6CYP1A2SMN1; SMN2MAPTCYP3A4
SCHEMBL10244037 0.79 CYP1A2 (0.46) CYP2D6CYP1A2SMN1; SMN2MTNR1AMTNR1B
SCHEMBL10243651 0.78 RAB9A (0.34) EPHX1CYP2D6CYP1A2SMN1; SMN2MTNR1A
SCHEMBL10244535 0.77 KMT2A (0.37) CYP2D6CYP1A2SMN1; SMN2CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 EPHX1 1924/4885REN 478/4885CYP2D6 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.