SCHEMBL1024430

SCHEMBL1024430

Cc1cc(C)c(C(=O)c2ccccc2P=O)c(C)c1.[NaH]

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.40
MEN1 O00255 3/20 0.40
HPGD P15428 4/20 0.39
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
METAP2 P50579 1/20 0.36
ABCB1 P08183 1/20 0.35
CRHR1 P34998 1/20 0.34
ALDH1A1 P00352 4/20 0.34
POLB P06746 1/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21831855 1.00 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL82365 0.98 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL1024555 0.97 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
Ammonia Solution, Strong SCHEMBL3101939 0.97 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
Water SCHEMBL25255612 0.97 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL28205455 0.95 ALDH1A1 (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL28106357 0.89 KMT2A (0.35) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL28560287 0.87 KMT2A (0.41) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL1830534 0.85 CYP3A4 (0.41) KMT2AMEN1HPGDLMNAALDH1A1
Hydrogen Sulfide SCHEMBL28875010 0.84 KMT2A (0.37) KMT2AMEN1HPGDLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same KURARAY CO., LTD. (JP) 2024-07-09 US disclosed
WO-2024096019-A1 DENTAL ADHESIVE COMPOSITION クラレノリタケデンタル株式会社 2024-05-10 WO disclosed
WO-2024053223-A1 CARIOUS TOOTH STRUCTURE RECOVERY AGENT, AND DENTAL ADHESIVE KIT クラレノリタケデンタル株式会社 2024-03-14 WO disclosed
EP-2979679-B1 CURABLE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2023-11-29 EP disclosed
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom KURARAY CO., LTD. (JP) 2023-11-14 US disclosed
WO-2023191112-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY クラレノリタケデンタル株式会社 2023-10-05 WO disclosed
WO-2023190931-A1 RESIN COMPOSITION FOR STEREOLITHOGRAPHY クラレノリタケデンタル株式会社 2023-10-05 WO disclosed
WO-2023127934-A1 ENERGY-RAY-CURABLE COMPOSITION FOR THREE-DIMENSIONAL SHAPING USE, DENTAL STRUCTURE, MOUTHPIECE, TEETH-STRAIGHTENING MOUTHPIECE, AND METHOD FOR PRODUCING DENTAL STRUCTURE クラレノリタケデンタル株式会社 2023-07-06 WO disclosed
WO-2023120610-A1 DENTAL CURABLE COMPOSITION クラレノリタケデンタル株式会社 2023-06-29 WO disclosed
WO-2023042912-A1 METHOD FOR MANUFACTURING INTRAORAL APPLIANCE EQUIPPED WITH COATING, AND INTRAORAL APPLIANCE EQUIPPED WITH COATING クラレノリタケデンタル株式会社 2023-03-23 WO disclosed
US-20100048761-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION KURARAY MEDICAL INC. (JP) 2010-02-25 US disclosed
US-20100048762-A1 COMPOSITION AND DENTAL MATERIAL KURARAY MEDICAL INC. (JP) 2010-02-25 US disclosed
US-20100036075-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION KURARAY MEDICAL INC. (JP) 2010-02-11 US disclosed
EP-2133368-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-12-16 EP disclosed
EP-2112177-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2112178-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2108663-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
EP-2108664-A1 COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
EP-2070935-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE Kuraray Medical Inc. (JP) 2009-06-17 EP disclosed
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same KABUSHIKI KAISHA SHOFU 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom WASF2, COPE, ARCN1 KMT2A 2942/4885MEN1 3152/4885HPGD 878/4885
US-20100048761-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION WDR82, PWWP2B, WDR5 KMT2A 2288/4885MEN1 2863/4885HPGD 319/4885
US-20100048762-A1 COMPOSITION AND DENTAL MATERIAL PHOSPHO1, PDS5B, ITGB5 KMT2A 1690/4885MEN1 4053/4885HPGD 1766/4885
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same POLQ, GAK, CAD KMT2A 1026/4885MEN1 3924/4885HPGD 1024/4885
US-12030970-B2 Curable composition and stereolithographic resin composition comprising same ARL1, ASH2L, VCL KMT2A 1501/4885MEN1 2530/4885HPGD 3840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.