SCHEMBL1024555

SCHEMBL1024555

Cc1cc(C)c(C(=O)c2ccccc2P=O)c(C)c1.[KH]

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.40
MEN1 O00255 3/20 0.40
HPGD P15428 4/20 0.39
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
METAP2 P50579 1/20 0.36
ABCB1 P08183 1/20 0.35
CRHR1 P34998 1/20 0.34
ALDH1A1 P00352 4/20 0.34
POLB P06746 1/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82365 0.98 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
Water SCHEMBL25255612 0.97 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
Ammonia Solution, Strong SCHEMBL3101939 0.97 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL1024430 0.97 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL21831855 0.97 KMT2A (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL28205455 0.95 ALDH1A1 (0.40) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL28106357 0.89 KMT2A (0.35) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL28560287 0.87 KMT2A (0.41) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL1830534 0.85 CYP3A4 (0.41) KMT2AMEN1HPGDLMNAALDH1A1
Hydrogen Sulfide SCHEMBL28875010 0.84 KMT2A (0.37) KMT2AMEN1HPGDLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023190931-A1 RESIN COMPOSITION FOR STEREOLITHOGRAPHY クラレノリタケデンタル株式会社 2023-10-05 WO disclosed
WO-2023042915-A1 STEREOLITHOGRAPHY PLATE DENTURE MANUFACTURING KIT, AND METHOD FOR MANUFACTURING PLATE DENTURE クラレノリタケデンタル株式会社 2023-03-23 WO disclosed
WO-2023042913-A1 METHOD FOR PRODUCING DENTURE クラレノリタケデンタル株式会社 2023-03-23 WO disclosed
WO-2023042912-A1 METHOD FOR MANUFACTURING INTRAORAL APPLIANCE EQUIPPED WITH COATING, AND INTRAORAL APPLIANCE EQUIPPED WITH COATING クラレノリタケデンタル株式会社 2023-03-23 WO disclosed
CN-115038730-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2022-09-09 CN disclosed
CN-114430750-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2022-05-03 CN disclosed
CN-113906068-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2022-01-07 CN disclosed
CN-108289794-B Dental adhesive 可乐丽则武齿科株式会社 2021-10-01 CN disclosed
WO-2021162007-A1 RESIN COMPOSITION FOR STEREOLITHOGRAPHY クラレノリタケデンタル株式会社 2021-08-19 WO disclosed
CN-113226247-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2021-08-06 CN disclosed
US-20100056665-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL KURARAY MEDICAL INC. (JP) 2010-03-04 US disclosed
US-20100048762-A1 COMPOSITION AND DENTAL MATERIAL KURARAY MEDICAL INC. (JP) 2010-02-25 US disclosed
US-20100048761-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION KURARAY MEDICAL INC. (JP) 2010-02-25 US disclosed
US-20100036075-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION KURARAY MEDICAL INC. (JP) 2010-02-11 US disclosed
EP-2133368-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-12-16 EP disclosed
EP-2112177-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2112178-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2108663-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
EP-2108664-A1 COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same KABUSHIKI KAISHA SHOFU 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048761-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION WDR82, PWWP2B, WDR5 KMT2A 2288/4885MEN1 2863/4885HPGD 319/4885
US-20100048762-A1 COMPOSITION AND DENTAL MATERIAL PHOSPHO1, PDS5B, ITGB5 KMT2A 1690/4885MEN1 4053/4885HPGD 1766/4885
US-20090105361-A1 Camphorquinone Derivative Having Acylphosphine Oxide Group, Photopolymerization Catalyst And Photo/Chemical Polymerization Catalyst Containing The Same And Hardenable Composition Contaning The Same POLQ, GAK, CAD KMT2A 1026/4885MEN1 3924/4885HPGD 1024/4885
US-20100056665-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL ITGA1, COL1A1, MACF1 KMT2A 1150/4885MEN1 1533/4885HPGD 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.