SCHEMBL1024732

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1027433	0.85	KDR (0.58)	KCNMA1HDAC1RAB9ANPC1HTT
	SCHEMBL4544559	0.82	GAA (0.66)	KCNMA1ITKHDAC1RAB9ANPC1
	SCHEMBL20897514	0.78	MAPK1 (0.56)	KCNMA1HDAC1RAB9ANPC1MAPK1
	SCHEMBL7292413	0.78	HSD17B2 (0.58)	KCNMA1RAB9ANPC1ALDH1A1GLA
	SCHEMBL16455939	0.77	RAB9A (0.59)	KITSRCFLT3ITKRAB9A
	SCHEMBL12203153	0.77	NPC1 (0.59)	KITSRCFLT3ITKRAB9A
	SCHEMBL7302704	0.77	ALDH1A1 (0.55)	HDAC1RAB9ANPC1ALDH1A1GLA
	SCHEMBL6030714	0.76	KCNMA1 (0.56)	KCNMA1HDAC1RAB9ANPC1ALDH1A1
	SCHEMBL13483900	0.76	GAA (0.76)	RAB9ANPC1ALDH1A1MAPK1HTT
	SCHEMBL1687872	0.75	TRPV1 (0.73)	RAB9ANPC1MAPK1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.